Bone mass is known to vary as a result of age, sex, behavior, and diet; however, little is known about the differences between populations. This study’s objective is to analyze cortical and trabecular bone structure in the proximal femur and to examine differences related to ethnicity and behavior. MicroCT scans were used to collect data from two Native American populations, the forager Black E...

Microarchitecture of trabecular bone is a very important component of bone quality in osteoporosis and a determinant of vertebral fracture in men with low bone mineral density (BMD). In contrast to women, male osteoporosis is, in most cases, secondary. The relationships between microarchitecture and different risk factors have never been evaluated in men. About 152 men with low BMD at the lumba...

Background: Trabecular Bone Score (TBS) is an index of bone microarchitecture that provides additional skeletal information to areal Mineral Density (aBMD). Recently TBS data has been used optimize the Fracture Risk Assessment Tool (FRAX) predictive value. Aim this study was evaluate clinical value on FRAX algorithm.

A homogenization sampling procedure is introduced which allows computation of effective trabecular bone stiffness and individual trabecula level stress based on precise models of trabecular bone architecture. Three-dimensional digitized images of 53 trabecular bone specimens with a resolution of 50 microns per voxel were directly converted into three-dimensional finite element meshes by making ...

Skeletal loading enhances cortical and trabecular bone properties. How long these benefits last after loading cessation remains an unresolved, clinically relevant question. This study investigated long-term maintenance of loading-induced cortical and trabecular bone benefits in female C57BL/6 mice and the influence of a surgically induced menopause on the maintenance. Sixteen-week-old animals h...

introduction: this study aims to evaluate the dentomaxillofacial radiographic changes in end stage renal disease (esrd) patients who were on hemodialysis. methods: parathyroid hormone (pth), calcium, phosphorus and alkaline phosphatase (alp) measurements, as well as panoramic and periapical radiographs were obtained from seventy four patients with a history of end stage renal disease (esrd). re...

Iliac crest trabecular bone volume and structure have been studied in bone biopsy specimens from 48 patients with classical or definite rheumatoid arthritis, none of whom had received steroids. Results were compared with those obtained from healthy controls matched for age and sex. The mean trabecular bone volume in female patients aged 34-50 years was significantly lower than in controls (p le...

The postcranial skeleton of modern Homo sapiens is relatively gracile compared with other hominoids and earlier hominins. This gracility predisposes contemporary humans to osteoporosis and increased fracture risk. Explanations for this gracility include reduced levels of physical activity, the dissipation of load through enlarged joint surfaces, and selection for systemic physiological characte...