Plasticity and reciprocity of breast cancer cells to various extracellular matrice (ECMs) are three-dimensionally analyzed in quantitative way in a novel and powerful microfluidic in vitro platform. This successfully demonstrates the metastatic potential of cancer cells and their effective strategies of ECM proteolytic remodeling and morphological change, while interacting with other cells and ...

Figure 4: The working system according to REFA _____________________________________________ 24 Figure 5: Areas of influence on the product development process [Ehrlenspiel 95, pg. 121] _____________ 25 Figure 6: Influencial areas of the product development process ___________________________________ 27 Figure 7: Reference Matrice of Concurrent Engineering (RMCE) _______________________________...

Due to the changes which may occur in their parameters, systems are usually demonstrated by some subsystems for different conditions. This paper employs Modified Petri Nets (MPN) to model theses subsystems and makes it simple to analyze them. In this method, first, the continuous transfer function is converted to a discrete transfer function and then, by MPN, system is modeled and analyzed. All...

In this paper a class of nonparametric transfer function models is proposed to model nonlinear relationships between 'input' and 'output' time series. The transfer function is smooth with unknown functional forms, and the noise is assumed to be a stationary autoregressive-moving average (ARMA) process. The nonparametric transfer function is estimated jointly with the ARMA parameters. By modelin...

Direct volume rendering has been an active area of research for over two decades. Transfer function design remains a difficult task since current methods, such as traditional 1D and 2D transfer functions are not always effective for all datasets. Various 1D or 2D transfer function spaces have been proposed to improve classification exploiting different aspects, such as using the gradient magnit...

over time but instead depends partly on the elapsed time between individual input events. The biophysical mechanisms underlying this shortterm synaptic plasticity are numerous and complex (29). As a result of such variety, different synapses supplied with the same temporal pattern of inputs may respond very differently. Thus a synapse does not simply transmit impulses from the presynaptic to th...