Malaria is the vector-transmitted disease that causes the highest morbidity and mortality in humans. Motivated by the known influence of sickle-cell anemia on the morbidity and mortality of malaria-infected humans, we study the effect of malaria on the genetic composition of a host (human) population where sickle-cell anemia is prevalent and malaria is endemic. The host subpopulations are there...

Abstract Background Studies of the malaria parasites infecting various non-human primates (NHPs) have increased our understanding origin, biology and pathogenesis human Plasmodium parasites. This review considers major discoveries concerning NHP parasites, highlights their relationships with impact that this may on attempts to eradicate disease. Results The first description dates back early 20...

BACKGROUND This study aimed at determining the prevalence and associated risk factors for asymptomatic malaria parasitaemia and anemia among blood donors in a private medical laboratory in Benin City, Nigeria. METHODS Venous blood was collected from a total of 247 blood donors. Malaria status, ABO, Rhesus blood groups and hemoglobin concentration of all participants were determined using stan...

Transfusion-transmitted malaria is rare, but it may produce severe problem in the safety of blood transfusion due to the lack of reliable procedure to evaluate donors potentially exposed to malaria. Here, we evaluated a new enzyme-linked immunosorbent assay malaria antibody test (ELISA malaria antibody test, DiaMed, Switzerland) to detect antibodies to Plasmodium vivax (the indigenous malaria) ...

OBJECTIVE To evaluate blood banks in the Brazilian Amazon region with regard to structure and procedures directed toward the prevention of transfusion-transmitted malaria (TTM). METHODS This was a normative evaluation based on the Brazilian National Health Surveillance Agency (ANVISA) Resolution RDC No. 153/2004. Ten blood banks were included in the study and classified as 'adequate' (≥80 poi...

Abstract This study aimed to evaluate the prevalence and trends of transfusion-transmitted infections (TTIs) in two hospitals Riyadh, as well judge best type tests ensure blood transfusion safety. By using serological nucleic acid test (NAT) tests, these donors were screened for human immunodeficiency virus (HIV), hepatitis C (HCV), B (HBV), T-lymphotropic 1 (HTLV-1), 2 (HTLV-2), syphilis, mala...

Introduction. Malaria is currently one of the most prevalent parasite-transmitted diseases caused by parasites of the genus Plasmodium. Misidentification of human malaria parasites especially P. knowlesi based on microscopic examination is very common. The objectives of this paper were to accurately identify the incidence of human malaria parasites in the interior division of Sabah, Malaysian B...

Addressing risk of imported malaria is complicated by 5 human species of Plasmodium, semi-immunity in donors with long-term exposure, increasing travel and immigration, changing risk in endemic areas, and limitations of screening assays. To gain insight into policy formulation, we have compiled epidemiologic data from 5 countries with different policies involving either deferral (the United Sta...

PROBLEM/CONDITION Malaria in humans is caused by intraerythrocytic protozoa of the genus Plasmodium (i.e., P. falciparum, P. vivax, P. ovale, and P. malariae). These parasites are transmitted by the bite of an infective female Anopheles species mosquito. The majority of malaria infections in the United States occur among persons who have traveled to areas with ongoing malaria transmission. In t...