Immense levels of data and the complexity of current logistics networks have made software support indispensable. Recurring calculations in network design and transportation planning can be automated with the help of planning software. Furthermore sophisticated algorithms are available to improve planning performance and reduce planning efforts. After a brief introduction of requirements in log...

Analysis of deformity and subsequent correction are the basis for many orthopaedic surgical procedures. In advanced cases of joint degeneration, arthroplasty may be the only available treatment option. Until recently, these analyses and preoperative surgical plans have been performed using standard radiographs, tracing paper, and/or plastic overlays. Numerous customized, commercially available,...

Cone beam computed tomography has created a specific revolution in maxillofacial imaging, facilitating the transition of diagnosis from 2D to 3D, and expanded the role of imaging from diagnosis to the possibility of actual planning. There are many varieties of cone beam computed tomography-related software available, from basic DICOM viewers to very advanced planning modules, such as InVivo Ana...

The treatment planning software TRiP98 [1, 2, 3] is successfully used in the ion therapy project at GSI. A crucial part of the treatment planning is the particle number optimization in order to achieve a target dose distribution as close as possible to the prescribed biological dose distribution. The optimization task can be expressed mathematically by the minimization of a multidimensional obj...

From 1997 until 2008 about 440 cancer patients were successfully treated in the ion therapy project at GSI. The patient treatment planning was performed with the software TRiP [1, 2]. A crucial part of the treatment planning is the particle number optimization with the goal to achieve a target dose distribution as close as possible to the prescribed biological dose distribution. The optimizatio...

Background/introduction Non-invasive ablation and hyperthermia treatments of abdominal organs using High Intensity Focused Ultrasound (HIFU) still impose severe challenges. Especially for liver and kidney treatments, the target motion and accessibility over the entire respiratory cycle make the application of HIFU difficult. To allow for a safe, effective, and efficient treatment, detailed plan...

In the GSI therapy pilot project from 1997 until 2008 about 440 cancer patients were successfully treated with carbon ions. Due to the promising healing rates the clinical radiotherapy facility HIT was launched and opened in 2009. Nevertheless, research and improvements of heavyion therapy are still in progress at GSI. For patient treatment planning the software TRiP [1, 2] is used. An essentia...

The Local Effect Model (LEM) represents an integral part of the heavy ion treatment planning software TRiP98 to calculate the biologically equivalent dose. Recently, the incorporation of cluster effects of single strand breaks at large local doses around the center of ion tracks was shown to be of particular importance for the prediction of the relative biological effectiveness (RBE) of the ini...