OBJECTIVE To describe the outcomes of retreatment in tuberculosis patients receiving the regimen known, in Brazil, as regimen 3 (streptomycin, ethambutol, ethionamide, and pyrazinamide for 3 months + ethambutol and ethionamide for 9 months) after treatment failure with the basic regimen (rifampin, isoniazid, and pyrazinamide for 2 months + rifampin and isoniazid for 4 months). METHODS A descr...

background: adequate self-care in diabetes causes quality of life promotion and decreases the number of inpatient cases. the health locus of control theory is used to assess adherence to diabetes regimen in some studies in developed countries. the purpose of this study was to determine the status of diabetes locus of control in a sample of diabetic patients in iran and investigation of it's rel...

we aimed to compare acceptability of levonorgestrel with the yuzpe regimen among iranian women based on their side-effects and resulting changes in the amount and pattern of menses.five hundred twenty nine participants aged 15-49 having regular menses and one act of unprotected intercourse within 72 h were included in the double-blind, controlled trial in 2006-2007 and randomly assigned into ln...

the pharmacokinetic parameters of ceftazidime, a third generation cephalosporin, were investigated in six buffalo calves after single intravenous (iv) and intramuscular (im) administration at a dose rate of 10 mg/kg body weight. ceftazidime concentrations in plasma and urine were determined by microbiological assay. ceftazidime disposition was best fitted by a two-compartmental and a one-compar...

pyricularia oryzae (tel. magnaporthegrisea) is currently used as a fungal model for plantmicrobeinteraction studies as well as an indicative model for anticancer drug discovery. thepresent study introduces the optimal condition in which p. oryzae grows and sporulates beston common culture media. we have considered three fungal culture media, i.e. pda, pca andwa, based on which p. oryzae sporula...

Background: The rate of Helicobacter pylori (H.pylori) eradication in dyspeptic patients using bismuth- based triple therapy is low due to bacterial that are resistant to antibiotics. The results of recent studies regarding levofloxacin have been encouraging, but the high cost of treatment prevents its routine administration. We, therefore, performed the present double-blind clinical trial to c...

A recent observational study of HIV patients in Germany suggests that treatment naïve patients that are in a more advanced stage of their disease are more likely to receive a treatment regimen based on a boosted protease inhibitor (PI/r) compared with a non-nucleoside reverse-transcriptase-inhibitor (NNRTI) base regimen. To validate those results we analysed claims data of seven German sickness...

b a c k g r o u n d & aim: today, one of the leading causes of pathogenicity and mortality in patients undergoing hemodialysis is their failure to follow the treatment plan. the present research was con- ducted to compare effects of patient-centered  education with family-centered  education on adher- ence with the treatment program. methods & materials: this clinical trial was performed betwee...

BACKGROUND The standard caspofungin treatment regimen (50 mg/day after a 70-mg dose on day 1) is effective and well tolerated for the treatment of invasive candidiasis, but experience with higher doses of caspofungin is limited. We evaluated the safety and efficacy of caspofungin at 3 times the standard dosing regimen. METHODS Patients with proven invasive candidiasis were randomized to recei...