PURPOSE Structural changes are well known to occur in the cornea after injury. The aim of this study was to investigate collagen orientation changes in the cornea during a short-term wound healing process. METHODS Seven bovine corneas were injured using a penetrating 5 mm biopsy punch and were subsequently organ cultured for up to two weeks. Six uninjured corneas acted as controls. The trephi...

BACKGROUND Non-Hodgkin lymphoma (NHLs) are a heterogeneous group of lymphoid neoplasms, characterized by an irregular pattern of spread and may present with extranodal involvement This study was conducted to determine the frequency and pattern of Bone marrow involvement on trephine biopsy in cases of Non-Hodgkin lymphoma (NHL). METHODS This cross sectional study was conducted in Pathology dep...

which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. A 68-year-old woman presented with rapidly growing multiple lymphadenopathy, night fever, weight loss, and drenching sweat. Physical examination revealed enlarged liver and spleen. Blood tests revealed pancytopenia, elevated levels of lactate dehydrogenase, ...

BACKGROUND Disseminated tuberculosis (TB) is a life-threatening condition which is often a challenge to diagnose. When to use bone marrow biopsies to diagnose disseminated TB in paediatrics is always a dilemma, from both a clinical and laboratory perspective, as there are no clear guidelines. Our study primarily aims to evaluate the role of routine bone marrow biopsies, and to compare periphera...

Bone marrow examination is commonly used in the evaluation of hemato-oncological disorders and in patients with cancer of solid organs to detect metastases. This study reviews clinical, hematological and pathological data of nine cases with bone marrow metastases from solid tumors. The significance of bilateral bone marrow aspirations and biopsy has also been highlighted. Out of 784 bone marrow...

INTRODUCTION Bone marrow examination is a useful investigative tool for the diagnosis of many hematological and nonhematological disorders. Bone marrow aspiration (BMA) provides information about the numerical and cytological features of marrow cells, whereas bone marrow trephine biopsies (BMB) provide excellent appreciation of spatial relationships between cells and of overall bone marrow stru...