نتایج جستجو برای: trf1
تعداد نتایج: 365 فیلتر نتایج به سال:
Recently, a second appeal decision from the Regional Federal Court of the 1 st Area (TRF1) opened again the debate about the practice of acupuncture in Brazil. In this action, the Federal Registration Board of Medicine questions the legitimacy of the resolutions of expertise in acupuncture of the Registration Boards of Physical Therapy, Occupational Therapy, Nursing, Psychology, Speech Patholog...
Yet another protein has been added to the crowd of players found at the ends of chromosomes. Known variously as PTOP, PIP1 or TINT1, this negative regulator of telomere length connects some of the key proteins already known to be present - TRF1, TIN2, POT1, and TRF2 - and adds even more complexity to telomere protein interactions.
PURPOSE Human telomeres, which are composed of long, repetitive sequences of TTAGGG and a variety of proteins, function as a protective structure capping the ends of chromosomes. Telomere dysfunction plays important roles in cancer initiation and progression. TRF1, TRF2, POT1, and RAP1 are four major telomere proteins that regulate telomere stability and telomere length. We hypothesized that th...
PURPOSE Telomere shortening is an early event in bronchial carcinogenesis, preceding P53/Rb pathway inactivation and telomerase reactivation, and leading to DNA damage responses (DDR). As their inactivation in cancer increases genetic instability, our objective was to identify the chronology of telomere machinery critical events for malignant progression. EXPERIMENTAL DESIGN We have evaluated...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید