Environmental signals drive seed dormancy cycling in the soil to synchronize germination with the optimal time of year, a process essential for species' fitness and survival. Previous correlation of transcription profiles in exhumed seeds with annual environmental signals revealed the coordination of dormancy-regulating mechanisms with the soil environment. Here, we developed a rapid and robust...

reasonable adult dose and, for this child, 1 mg kg. There are no available data concerning the likely absorption of corticosteroid from a topical preparation such as Eumovate in a child of this age; however, it would be a coincidence if this event were not involved in the development of GPP in this case. While unlikely to be a common occurrence in everyday clinical practice it does appear that ...

BACKGROUND AND AIMS Differential diagnosis of the group of benign trichoblastomas, trichofolliculomas, trichoadenomas and trichoepitheliomas, and basal cell carcinomas (BCCs) is troublesome for the clinician as well as the pathologist, especially when only small biopsy specimens are available. Here we investigated whether CD34 expression might be of assistance. METHODS Thirty benign tumors of...

espanolEl sindrome de Brooke-Spiegler (SBS) es una genodermatosis poco frecuente, herencia autosomica dominante, con penetrancia y expresividad variables, que predispone a la produccion neoplasias anexiales. En clinica se caracteriza por aparicion simultanea progresiva cilindromas, tricoepiteliomas y, en ocasiones, espiradenomas. El SBS produce mutaciones el gen CYLD1 localizado cromosoma 16 fo...