Fluorinated copolymers bearing ammonium groups were prepared by radical copolymerization of fluorinated olefins (chlorotrifluoroethylene, hexafluoropropylene) with different vinyl ethers (2-chloroethyl, cyclohexyl, n-butyl, and ethyl vinyl ethers) followed by the cationization of these copolymers with trimethylamine. Copolymers were obtained in high yield (generally > 85 %), with molecular weig...

The protein stabilizing effects of the small molecule osmolyte, trimethylamine N-oxide, against chemical denaturant was investigated by NMR spin-relaxation measurements and model-free analysis. In the presence of 0.7 M guanidine hydrochloride increased picosecond-nanosecond dynamics are observed in the protein ribonuclease A. These increased fluctuations occur throughout the protein, but the mo...

OBJECTIVE This review aimed to summarize the relationship between intestinal microbiota metabolism and cardiovascular disease (CVD) and to propose a novel CVD therapeutic target. DATA SOURCES This study was based on data obtained from PubMed and EMBASE up to June 30, 2015. Articles were selected using the following search terms: "Intestinal microbiota", "trimethylamine N-oxide (TMAO)", "trime...

Abstract The oxidation of a series fatty alcohols to yield the corresponding aldehydes is performed using RuCl 3 ⋅ (H 2 O) x as homogeneous catalyst and inexpensive trimethylamine N ‐oxide (TMAO) oxygen source. reaction conditions were optimized for both high conversion selectivity.

Characterization of metabolites and microbiota composition from human stool provides powerful insight into the molecular phenotypic difference between subjects with normal weight those overweight/obesity. The aim this study was to identify potential metabolic bacterial signatures that distinguish overweight/obesity state in children/adolescents. Using 1 H NMR spectral analysis 16S rRNA gene pro...