Productivity, trophic structure, and energy flow in the steady-state ecosystems of Silver Springs, Florida W.M. Kemp a,∗, W.R. Boynton b a Horn Point Laboratory, Center for Environmental Science, University of Maryland System, Box 775, Cambridge, MD 21613, USA b Chesapeake Biological Laboratory, Center for Environmental Science, University of Maryland System, 1 Williams Street, Solomons, MD 206...

Aberrant formation of interstitial telomeric sequences (ITSs) promotes genome instabilities. However, it is unclear how aberrant ITS formation is suppressed in human cells. Here, we report that MLH1, a key protein involved in mismatch repair (MMR), suppresses telomeric sequence insertion (TSI) at intra-chromosomal regions. The frequency of TSI can be elevated by double-strand break (DSB) induce...

BACKGROUND AND AIM In Graves' hyperthyroidism, suppression of serum TSH after restoration of normal serum T4 and T3 with treatment has been attributed to binding of TSH-receptor antibodies to TSH receptors in the pituitary. Accordingly, the relationship between TSH and serum thyroid stimulating immunoglobulin (TSI) was examined during follow-up of patients with Graves' hyperthyroidism. SUBJEC...