Comprehensive new guidelines for screening, targeted testing, and treating latent tuberculosis infection (LTBI) in children and adolescents are presented. The recent epidemiology of TB and data on risk factors for LTBI are reviewed. The evidence-based recommendations provided emphasize the paradigm that children and adolescents should be screened for risk factors by using a risk-factor question...

BACKGROUND Cutaneous sensitivity to the tuberculin antigen is thought to indicate latent tuberculosis infection (LTBI). Some guidelines suggest treating end-stage renal disease (ESRD) patients for LTBI on the basis of tuberculin positivity. The prevalence of tuberculin sensitivity and cutaneous anergy in Indian patients with ESRD and the utility of the tuberculin test for predicting post-transp...

focus or foci to heal, and secondly, to prevent its spread and tuberculin aids in both these aims The essentials for success are laid down as individualization, size of dose, method of increase and interval" together with a full appreciation of the underlying disease conditions by the physician. The author pertinently remarks that the man who determines to try tuberculin should not do so to tes...

To estimate the annual risk of tuberculosis (TB) infection (ARTI) in Somalia a tuberculin survey was conducted in February/March 2006. Stratified cluster sampling was carried out within the 18 regions and 101 randomly selected primary schools. Tuberculin testing was done in 10 680 grade 1 schoolchildren. Transverse tuberculin reaction size was measured 72 hours later. The number of children wit...

In educational learning contexts, unlike typical contemporary laboratory paradigms, students have repeated opportunities to study and learn target material, thereby potentially allowing different sequences of testing and studying. We investigated learning and retention after several plausible sequences that were patterned on a classic memory paradigm. After initially reading a research methods ...

The immune response induced by vaccination with Bacille Calmette-Guérin (BCG) is not fully understood, and the interpretation of the tuberculin skin test (TST) is still under debate. This thesis was based on questions raised while implementing protective measures for healthcare workers and others at risk of exposure to tuberculosis (TB) in Sweden, a country where the prevalence of TB is low. Th...

Comprehensive new guidelines for screening, targeted testing, and treating latent tuberculosis infection (LTBI) in children and adolescents are presented. The recent epidemiology of TB and data on risk factors for LTBI are reviewed. The evidence-based recommendations provided emphasize the paradigm that children and adolescents should be screened for risk factors by using a risk-factor question...

At a recent meeting of the National Association for the Prevention of Tuberculosis, a special plea was put forward for a wholesale examination of children of school age, with a view to discovering signs of existing latent tuberculous infection. There was general agreement that in such a routine examination the tuberculin test must play an important part. and it is the purpose of this paper to d...

BACKGROUND An inverse association between tuberculin responses and atopy has been observed in Japanese children, indicating that BCG immunisation, subclinical exposure to Mycobacterium tuberculosis without clinical disease, or host characteristics may influence the T helper (Th) lymphocyte balance with decreased atopy as a result. This study was undertaken to determine whether tuberculin reacti...