Aldosterone has attracted significant consideration for its role in the progression of renal injury. Since apoptotic cell loss contributes to the deterioration of renal function, we examined the effect of aldosterone on tubular cell apoptosis. To determine dose and time course effect, human renal proximal tubular (HK2) cells were treated with aldosterone at different doses and for variable time...

The European Union is moving towards a sustainable, decarbonized, and circular economy. It has identified seven key value chains in which to intervene, with the battery vehicle chain being one of them. Thus, actions strategies for sustainability batteries need be developed. Since Life Cycle Assessment (LCA) strategic tool evaluating environmental sustainability, this paper investigates its appl...

BACKGROUND/AIMS Kidney abnormalities are one of the main chronic complications of sickle cell disease (SCD). The aim of this study is to investigate the occurrence of renal tubular abnormalities among patients with SCD. METHODS This is a prospective study with 26 SCD adult patients in Brazil. Urinary acidification and concentration tests were performed using calcium chloride (CaCl2), after a ...

Erythropoietin (EPO) can induce a series of cytoprotective effects in many non-hematopoietic tissues through interaction with the erythropoietin receptor (EPOR), but whether EPO can prevent the overproduction of reactive oxygen species (ROS) and apoptosis in diabetes remains unclear. Here, we report that renal tubular cells possess EPOR and that EPO reduces high glucose-induced oxidative stress...

distal renal tubular acidosis is a syndrome of abnormal urine acidification and is characterized by hyperchloremic metabolic acidosis, hypokalemia, hypercalciurea, nephrocalcinosis and nephrolithiasis. despite the presence of persistent hypokalemia, acute muscular paralysis is rarely encountered in males.here, we will report an eighteen year old male patient who presented with flaccid quadripar...

Ammonia is being considered as a promising alternative to hydrogen fuel in solid oxide cells (SOFCs) due its stability and ease of storage transportation. This study investigates the feasibility using ammonia tubular SOFC for shipborne unmanned aerial vehicles (UAVs). The paper develops 3D model tubular-anode-supported single cell conducts numerical simulations analyze impact different operatin...

Hamid Nasri1, MD; Mahmoud Rafieian-Kopaei2*, MD 1Department of Nephrology, Division of Nephro pathology, Isfahan University of Medical Sciences, Isfahan, 2Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran Received: Aug 22, 2013; Accepted: Sep 30, 2013; First Online Available: Dec 12, 2014 Acute renal failure (ARF) or acute kidney injury (AKI) may develo...