Nerve growth factor (NGF) facilitates reinnervation of perivascular nerves that regulate vascular tone and blood flow. This study investigated whether NGF prevents tumor growth by promoting neuronal regulation of tumor blood flow. The growth rate of DU145 prostate carcinoma cells subcutaneously implanted into nude mice was significantly inhibited by subcutaneous NGF administration. Significant ...

burkitt's lymphoma is a lymphatic tumor classified as non-hodgkin lymphoma with small non cleaved cells. the disease has an incidence of two cases per million patients in north america, and usually present with an intra-abdominal tumor, or enlarged cervical lymph nodes. massive amounts of peritoneal and plural fluid is rarely seen in these patients. a three year-old girl presented with massive ...

Heart failure and cancer are the deadliest diseases worldwide. Murine models for cardiac remodeling heart demonstrate that dysfunction promotes progression metastasis spread. Yet, no information is available on whether how tumor affects remodeling. Here, we examined following transverse aortic constriction (TAC) in presence or absence of proliferating cells. We show tumor-bearing mice, two diff...

introduction: epidermal growth factor receptor (egfr) has been shown to play a critical role in tumor cell growth and its overexpression has been observed in many epithelial tumors. in the field of cancer vaccine research, displaying the peptide mimotope on the surface of phage particles has shown promising results. methods: in this study using m13-pviii phage display system, two constructs wer...