Strong experimental evidence has indicated that tumor growth belongs to the molecular beam epitaxy universality class. This type of growth is characterized by the constraint of cell proliferation to the tumor border and the surface diffusion of cells at the growing edge. Tumor growth is thus conceived as a competition for space between the tumor and the host, and cell diffusion at the tumor bor...

that metastasis often occurs early in tumor progression. In early stage breast cancer, for example, a significant percentage of patients exhibit circulating tumor cells (CTC's) and disseminated bone marrow tumor cells (DTC's) [1,2]. More direct experimental evidence for " early metastasis " has been observed in studies of transgenic mice expressing a cancer-causing oncogene where the primary ca...

We present a unique case of tumoral calcinosis (TC) with airway involvement and a novel technique for debridement. TC is a rare disorder, characterized by calcified tumors and dysfunction of large joints. To date there have been no reports of calcification involving the airway. CD is a 43 year old male with a long history of TC who developed dysphagia prompting otolaryngic evaluation. He was fo...

Background: Presurigical planning for glioma tumor resection and radiotherapy treatment require proper delineation of tumoral and peritumoral areas of brain. Diffusion tensor imaging (DTI) is the most common mathematical model applied for diffusion weighted MRI data. Neurite orientation dispersion and density imaging (NODDI) is another mathematical model for DWI data modeling.Objective: We stud...