BACKGROUND Thiopurines are an effective treatment for moderate to severe inflammatory bowel disease [IBD] and can be used safely in pregnancy. Combining allopurinol with a lower dose of thiopurine can improve clinical efficacy and bypass some adverse reactions associated with thiopurine monotherapy. Data on allopurinol in pregnancy are scarce. We report on a total of 13 cases where thiopurine a...

OBJECTIVE Fetal vessel thrombosis has been related to pregnancy complications and adverse neonatal outcomes in singleton pregnancies, but the clinical and pathologic characteristics of fetal thrombosis in twin pregnancy are still ill defined. METHODS To clarify the characteristics of fetal thrombosis in twins, we reviewed the histology slides and medical records of live-born infants of twin p...

We are not aware of a report detailing the complex obstetrical and medical management of twin pregnancy in the context of HIV infection and early post-liver transplantation period. Here we describe the successful outcome of a twin pregnancy in a 28-year-old HIV-positive female receiving antiretroviral therapy and immunosuppressive therapy who was the recipient of a liver transplant for previous...

Anencephaly is a lethal diagnosis. In the unique situation of a twin pregnancy discordant for anencephaly, early ultrasound diagnosis based on the discrepancy in the appearance of the heads can facilitate management and potentially decrease morbidity and mortality for the unaffected twin. We report two such cases of dichorionic, diamniotic twin pregnancies and provide a review of the literature.

To cite: Martins CF, Santos AV, Miranda M, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2014-207688 DESCRIPTION A 32-year-old primigravida referred at 22 weeks with contractions. Ultrasound examination showed a 20 mm cervix and a monochorionic diamniotic pregnancy with one structurally normal fetus with hydramnios and a second twin anencephalic and acar...

dicephalic parapagus tribrachius conjoined twin is a very rare condition. we present a case of 5-days-old male dicephalic parapagus conjoined twins. the conjoined twins were diagnosed in 4(th) month of pregnancy by ultrasonography. the pregnancy terminates at 36 weeks by cesarean section and triplets were born. the babies were male conjoined twins and another healthy male baby. many congenital ...

Background: The impact of vanishing twin (VT) syndrome on obstetric outcome is currently unknown. The aim of this study was to compare obstetric and neonatal outcomes of VT with singleton and twin deliveries after assisted reproduction and to evaluate the impact of VT on pregnancy outcome. Methods: We analyzed 130 births at our hospital between January 2000 and February 2012 that resulted from ...

This study examines the value of assessing inter-twin membrane folding in monochorionic twin pregnancies in the prediction of twin-to-twin transfusion syndrome. In 83 monochorionic twin pregnancies ultrasound scans were carried out at 10-14, 15-17 and 19-21 weeks to investigate folding of the inter-twin membrane as an early sonographic feature of inter-twin discrepancy in amniotic fluid volume....

Congenital candidemia sepsis is a serious condition especially for the prematurity. Early recognition is always not the scenario and this leads to high morbidity and mortality. Twin pregnancy complicates the problems further. This report presents a case of congenital candidiasis in a twin preterm and literatures review of five twin pairs with the same scenario. In conclusion, for twin prematuri...