A leg ulcer is generally considered to be a wound with tissue loss on the lower leg, including the foot, which has not healed within four to six weeks of injury or opening of the wound. Internationally chronic venous insufficiency is the causative aetiology for 50% of all leg ulcers, with mixed venous/arterial disease accounting for up to another 20% of ulcers. Arterial ulcers, diabetic ulcers ...

Raynaud, digital ulcers and calcinosis are frequent manifestations of patients with systemic sclerosis. Digital ulcers are seen in more than half of the patients with scleroderma. Hospitalizations, ischemic complications and impairment of hand function are frequently observed in patients with digital ulcers, especially if treatment is delayed. Rapid and intensive treatment escalation in patient...

This study evaluated the use of phototherapy in the healing of mixed leg ulcers in two diabetic patients (type 2) with arterial hypertension. The device had probe 1 (one 660 nm LED, 5 mW) applied in 3 ulcers and probe 2 (32 890 nm LEDs associated with 4 660 nm LEDs, 500 mW) in 6 ulcers. After asepsis, ulcers were treated with probes to 3 J/cm2, 30 sec per point, twice a week, followed by topica...

PURPOSE To summarize clinical and empirical knowledge about pressure ulcers in infants and children and to describe an approach developed at Children's Hospital, Boston, to prevent and manage pressure ulcers. POPULATION Acutely ill children with potential or actual alteration in skin integrity due to pressure ulcers. CONCLUSIONS The three-pronged approach for pressure ulcer prevention and m...

Chronic leg ulcers are a common medical problem among elderly patients and have a dramatic impact on quality of life as a result of pain, disability, and social isolation. Regardless of their cause, chronic leg ulcers remain difficult to treat. In recent years, there has been increasing interest in the use of honey as a therapeutic agent. Objective: To evaluate the efficacy of honeybased dressi...

The ingestion of non-steroidal anti-inflammatory drugs (NSAID) in 272 patients with bleeding or perforated peptic ulcer was compared with 272 age/sex matched controls. A significantly higher proportion of patients with gastric ulcers had received NSAID than those with duodenal ulcers. Twelve of 90 (13%) patients admitted with bleeding duodenal ulcers had received NSAID compared with 11 of 26 (4...

Venous leg ulcers, the most common form of leg ulcers, are relevant to the pathogenicity of pericapillary fibrin cuff. Sarcoidosis, a multiorgan granulomatous disease, causes fibrin deposition in tissues. We report a case of a 50-year-old man with venous leg ulcers coexisting with sarcoidosis. On the basis of the histologic findings, we propose the hypothesis that sarcoidosis patients are prone...

Pseudomonas aeruginosa colonizes 20-30% of all venous leg ulcers. Hypothetically, P. aeraginosa could release proteases and cytotoxic substances in the environment of chronic ulcers, thus negatively affecting the wound-healing activity in this patient group. Here we show that P. aeruginosa isolates from leg ulcers exhibit a highly variable expression of the proteinases elastase and alkaline pro...

Acute ulcers of the gastric mucosa are found in a large percentage of dogs and cats dying after adrenalectomy. These ulcers seem to develop during the moribund period. They are apparently peptic ulcers forming at the site of local hemorrhages in the gastric mucosa. They are true acute ulcers, usually penetrating to the muscularis mucosa with a total loss of epithelium. They develop in the absen...

Abomasal ulcers are an economic concern for the calf raising industries. Many factors have been attributed to the development of ulcers, such as coarse feed, environmental stress, vitamin and mineral deficiencies, and bacterial infections. However, unlike human ulcers no one factor has been proven to have a significant relationship to abomasal ulcers in calves. Therefore, management of this dis...