Background: We aimed to establish a novel diagnostic model for kidney diseases by combining artificial intelligence with complete mass spectrum information from urinary proteomics. Methods: enrolled 134 patients (IgA nephropathy, membranous and diabetic disease) 68 healthy participants as controls, total of 610,102 spectra their proteomic profiles. The training data set (80%) was used create us...

This paper presents a brief introduction to proteomics and defining the concept of proteomics. After that, listing some important techniques that used in from 2010 2020. It explores proteomics’ advantages limitations, how it has advanced this past decade. Finally, outlines evolution its methods, modifications made period. aim is analyse identify changes transitions experienced

introduction: during the last 3 decades, human is exposed to extremely low frequency electromagnetic fields (elf-emf) emitted by power lines and electronic devices. it is now well accepted that elf-emf are able to produce a variety of biological effects, although the molecular mechanism is unclear and controversial. investigation of different intensities effects of 50 hz elf-emf on cell morphol...

The increasing number of patients suffering from chronic renal failure represents one of the major challenges to which nephrologists are faced worldwide today. For a better therapeutic outcome of this disease earlier detection is urgently warranted in routine clinical practice. Urine is a kind of messenger of the urinary system function. Kidney damage or dysfunction results in release of peptid...

IMPORTANCE Infantile hemangiomas (IHs) vary substantially in localization and extent of tissue involvement, but IH biological progression is remarkably unique and predictable. Propranolol is an effective treatment for symptomatic IH, but its mechanism of action remains unknown and understudied. OBJECTIVE To compare excreted proteins in infants with IH being treated with propranolol vs prednis...