نتایج جستجو برای: urocortin
تعداد نتایج: 684 فیلتر نتایج به سال:
AIMS To document the haemodynamic, neurohormonal, and renal responses to Urocortin 2 (UCN2) infused in human heart failure (HF). METHODS AND RESULTS Eight male patients with HF [left ventricular ejection fraction (LVEF) < 40%, NYHA class II-III] received placebo and 25 [low dose (LD)] and 100 microg [high dose (HD)] of UCN2 intravenously over 1 h in a single-blind, placebo-controlled, dose-es...
Urocortin 1 (Ucn1) and urocortin 3 (Ucn3) are new members of the corticotrophin-releasing factor (CRF) peptide family. Ucn1 is a ligand for both the CRF type 1 receptors (CRF(1)Rs) and the CRF type 2 receptors (CRF(2)Rs), whereas Ucn3 is a high-affinity ligand for the CRF(2)Rs. Recently, we reported that Ucn3 microinjections into the medial nucleus tractus solitarius (mNTS) elicit decreases in ...
Abbreviations used in this paper: CRF, corticotropin-releasing factor; CRF1-LI, CRF1 receptor like immunoreactivity; CRF2-LI, CRF2 receptor like immunoreactivity; DMSO, dimethylsulfoxide; cDNA, complementary DNA; KRB, Krebs-Ringer buffer; mRNA, messenger RNA; PVN, paraventricular nucleus; RT-PCR, reverse transcription-polymerase chain reaction; SYN, synaptophysin; TTX, Tetrodotoxin; Ucn, urocor...
Stress and anxiety play a role in many psychological processes including social behavior. The present study examines the effects of urocortin II (UCN II) on spontaneous parental behavior in adult prairie voles (Microtus ochrogaster). UCN II was found to increase passive parental behavior in voles while not affecting any stress-related measures. Delineating the mechanism of this change will aid ...
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