14alpha-Demethylase (CYP51) is a key enzyme in all sterol biosynthetic pathways (animals, fungi, plants, protists, and some bacteria), catalyzing the removal of the C-14 methyl group following cyclization of squalene. Based on mutations found in CYP51 genes from Candida albicans azole-resistant isolates obtained after fluconazole treatment of fungal infections, and using site-directed mutagenes...

objective: the genus trichoderma comprises a great number of fungal strains that act as biological control agents, the antagonistic properties of which are based on the activation of multiple mechanisms. methods: trichoderma strains exert biocontrol against fungal phytopathogens either indirectly, by competing for nutrients and space, modifying the environmental conditions, or promoting plant g...

Microorganisms play a significant role in bioremediation of heavy metal contaminated soil and wastewater. In this study, heavy metal resistant fungi and bacteria were isolated from the soil samples of an electroplating industry, and the bioaccumulations of Cr(VI) and Ni(II) by these isolates were characterized to evaluate their applicability for heavy metal removal from industrial wastewaters. ...

Dalbergia odorifera T. Chen is a medium-sized evergreen tree that produces purple-brown heartwood called JiangXiang in traditional Chinese medicine, the formation process of which takes several decades. In this study, a standard culture method was used to isolate fungi from the wounded and normal stems of D. odorifera aiming to investigate the difference between the two types of wood. To charac...

PURPOSE OF REVIEW Comparative genome sequencing studies of human fungal pathogens enable identification of genes and variants associated with virulence and drug resistance. This review describes current approaches, resources, and advances in applying whole genome sequencing to study clinically important fungal pathogens. RECENT FINDINGS Genomes for some important fungal pathogens were only re...

HIV related opportunistic fungal infections (OFIs) continue to cause morbidity and mortality in HIV infected patients. The objective for this prospective study is to elucidate the prevalence and spectrum of common OFIs in HIV/AIDS patients in north India. Relevant clinical samples were collected from symptomatic HIV positive patients (n = 280) of all age groups and both sexes and subjected to d...

background and objectives: vulvovaginal candidiasis is a common fungal infection among women during reproductive ages. although, candida albicans is accounted as the main etiologic agent of vaginitis, non- albicans species have arisen during last years. resistant to antifungal drugs especially, fluconazole has been more reported by researchers from around the world. the aims of this study were ...

The fluctuation of Meloidogyne population density and the percentage of fungal egg parasitism were determined from July 2011 to July 2013 in two commercial organic vegetable production sites (M10.23 and M10.55) in plastic greenhouses, located in northeastern Spain, in order to know the level of soil suppressiveness. Fungal parasites were identified by molecular methods. In parallel, pot tests c...

one of the most important and elusive diseases of grapevine is esca disease. esca is a complex disease that comprises a combination of symptoms caused by various fungi including growth retardation, decrease in productivity and decline of the plant and usually affecting adult plants (8 to 10 years and older). the purpose of this research was to study the genetic variations of fungal agents assoc...