malaria is currently one of the most important causes of mortality in developing countries. high resistance to available antimalarial drugs has been reported frequently, thus it is crucial to focus on the discovery of new antimalarial drugs. artemisinin, an effective antimalarial medication, is isolated from various artemisia species. to identify the artemisia species producing high quantity of...

Background & Aims: SLC26A4 gene mutations are the second identifiable genetic cause of autosomal recessive nonsyndromic hearing loss (ARNSHL) after GJB2 mutations and are currently investigated in molecular diagnosis.In databases, several potential STR markers related to this region have been introduced. In this investigation, the characteristics and informativeness of D7S2425 CA repeat STR mar...

background and objective: serum creatinine is the most used endogenous marker of glomerular filtration rate (gfr), but it also has multiple limitations. therefore, some surrogate gfr markers, such as beta trace protein, have been introduced for gfr estimation. the aim of our study was to estimate gfr by serum beta trace protein using three available equations and compare them to dtpa gfr as the...

objective: the current methods for bladder cancer diagnosis suffer from low sensitivity and specificity. therefore, finding a novel tumor markers with high specificity and sensitivity is of great interest. micrornas (mirna, mir) are small endogenously-produced, non-coding rnas with an important role in regulating gene expression. recent studies show that mirnas expression profiles represent sig...

to determine the role of ddx3y gene in spermatogenesis and infertility in bulls, blood samples were collected from five infertile bulls (azoospermic; no sperm in the semen) at the animal breeding center in karaj, iran. the recommended human primers by eaa/eqmn were investigated using the blastn database for sts marker detection. alignment of sts marker genes with bovine genome was performed. pr...

to evaluate the genetic variations in eleven fennel populations in iran, 55 accessions were analyzed by srap markers. twelve primer combinations produced 171 polymorphic bands. the cumulative dendrogram delineated fennel accessions into five major groups in accordance to the geographical regions from which the populations were originated. about 43.57% of total genetic variation was detected amo...

die-back disease caused by paecilomyces variotti is one of the most destructive diseases of pistachio in iran. in this study, genetic diversity of paecilomyces variotti isolates was investigated with ssr marker, using six primers pairs. sampling was done from pistachio gardens in different geographical zones of kerman province during summer 2013. various fungal isolates were isolated from infec...

this article reviews the recently published data on the diagnosis of cancer with proteomics, including the major proteomics technologies and promising strategies for biomarker discovery and development.  most of the tumor markers are proteins that either numerically increase in response to the alteration of cancer conditions or are produced by cancer cells. however, they are natural compounds o...

the study of genetic variation and phylogenetic relationships is essential for the efficient selection of superior plant material and conducting introgression breeding programs. in iran, despite the wide geographical distribution of grasses no report is available on the genetic diversity and relationships of cool season grass populations. in this study amplified fragment length polymorphism (af...