Aim: To investigate the effect of adding oophorectomy on patients who underwent abdominal hysterectomy in perimenopausal period menopause, sexual function and mental status. Materials Methods: The study was designed prospectively. Women total bilateral salpingectomy (TAH+BS) salpingo-ophorectomy (TAH+BSO) for benign indications were included study. Three months after surgery, menopausal symptom...

Objective The aim of the present randomized placebo-controlled single-center study was to assess efficacy and safety a new vaginal gel (Meclon Idra - Alfasigma) in treatment vulvovaginal atrophy (VVA). is composed sea buckthorn (Hippophaë rhamnoides) oil, aloe vera, 18?-glycyrrhetic acid, hyaluronic acid glycogen. assessed whether can reduce VVA symptoms (vaginal dryness, itching, burning sensa...

Objective. This study aims to evaluate the effect of daily dietary nutritional supplement on somatic, psychological, and urogenital symptoms in postmenopausal women. Material and Methods. In this study 28 healthy, symptomatic, peri- and postmenopausal women of 47-67 years of age were allocated to use the nutritional supplement JuicePLUS+®. Primary research parameters: Menopause Rating Scale (MR...

The prevalence of vaginal atrophy is particularly high among women who have undergone treatment for gynecological cancers, since they significantly lower estrogen levels and altered microbiota. These patients often experience discomfort, dryness, pain, but rarely report this to a doctor. Such symptoms affect patients’ quality life might cause family breakdown. This article proposes safe therape...

Vulvovaginal atrophy (VVA) and dryness are common symptoms of the decline in endogenous production of estrogen at menopause and often result in dyspareunia. Yet while 10% to 40% of women experience discomfort due to VVA, it is estimated that only 25% seek medical help. The main goals of treatment for vaginal atrophy are to improve symptoms and to restore vaginal and vulvar anatomic changes. Tre...

Four hundred and twenty-one adult allogeneic haematopoietic stem cell transplant (HSCT) survivors participated in a cross-sectional study to assess sexual dysfunction and infertility post-transplant. Survey instruments included the Sydney Post-Blood and Marrow Transplant (BMT) Survey, Functional Assessment of Cancer Treatment (FACT) - BMT, the Depression, Anxiety, Stress Scales (DASS 21), the C...

BACKGROUND A modified form of high dose rate (HDR) brachytherapy has been developed called Axxent Electronic Brachytherapy (EBT). EBT uses a kilovolt X-ray source and does not require treatment in a shielded vault or a HDR afterloader unit. A multi-center clinical study was carried out to evaluate the success of treatment delivery, safety and toxicity of EBT in patients with endometrial cancer....

BACKGROUND Tamoxifen is generally considered a safe drug for Indian women with breast cancer. Indian women seem to tolerate tamoxifen therapy better than western women, but there are no data regarding safety and local adverse effect profiles in typical Indian populations. METHODS AND RESULTS A total of 3,000 case records of patients who had received tamoxifen daily for any period of time, bet...

Introduction: Premature Ovarian Failure (POF) is cessation of ovarian functions before the age of 40 years old with consequent cessation of menstruation. Objective of study: The aim of this study was to evaluate the association between Premature Ovarian Failure and sexual dysfunctions and outcome of management with tibolone. Patients and Methods: Thirty-one women with Premature Ovarian Failure ...

Stratospheric dryness J. Lelieveld, C. Brühl, P. Jöckel, B. Steil, P. J. Crutzen, H. Fischer, M. A. Giorgetta, P. Hoor, M. G. Lawrence, M. Milz, R. Sausen, G. P. Stiller, and H. Tost Max Planck Institute for Chemistry, J.J. Becherweg 27, 55128 Mainz, Germany Scripps Institution of Oceanography, UCSD, La Jolla, CA 92093-0221, USA Max Planck Institute for Meteorology, Bundesstrasse 53, 20146 Hamb...