Schiller-Duval body is a distinctive pathological structure seen in the endodermal sinus pattern of yolk sac tumor. This manuscript provides a concise review about this structure and the scientists behind it. *Corresponding author: Dr. Khalid Al Aboud, King Faisal Hospital, Makah, Saudi Arabia, P.O Box 5440, Makah 21955, Saudi Arabia, E-mail: [email protected] Received January 25, 2014; Accept...

MR images of pineal region tumors were analyzed in 26 patients with histologically proved tumors: seven germ-cell tumors, six astrocytomas, five teratomas, three pineoblastomas, two meningiomas, one dermoid, one epidermoid, and one metastasis. In an attempt to identify specific MR characteristics of these lesions, Gd-DTPA was administered to six patients. CSF and blood serum were assayed for al...

Adrenogenital syndrome, or so called congenital adrenal hyperplasia, is caused by a congenital insufficiency of the enzyme 21-hydroxylase, which is responsible for converting cortisol into cholesterol. Because of virilizing effect of androgens overproduction girls develop clitoral hypertrophy and persistent urogenital sinus (common channel for urethra and vagina). Surgical treatment is recommen...

Ovarian tumors are classified on the basis of tumor origin as epithelial tumors (serous and mucinous tumors, endometrioid and clear cell carcinomas, Brenner tumor), germ cell tumors (mature and immature teratomas, dysgerminoma, endodermal sinus tumor, embryonal carcinoma), sex cord-stromal tumors (fibrothecoma; granulosa cell, sclerosing stromal, and Sertoli-Leydig cell tumors), and metastatic ...

adenoid cystic carcinoma is an uncommon, slow growing malignant salivary gland tumor that is characterized by wide local infiltration, perineural spread, propensity to local recurrence anddistant metastasis. in this paper, the authors present a case of adenoid cystic carcinoma affecting the palate and involving the maxillary sinus in a 60‑year‑old male patient along with a brief reviewof litera...

  Littoral cell angioma is a splenic vascular tumor of splenic sinus lining cells that is considered benign in general. This report describes a case of littoral cell angioma with no malignant histological features. The lesion is composed of anastomosing vascular channels resembling splenic sinus; they are lined by endothelial cells which show mitotic activity very rare. Immunohistochemically, ...

Teratomas, the most common extragonadal germ cell tumor of childhood, involve at least two of the ectodermal, mesodermal, and endodermal layers. Of the teratomas seen in the first 2 months of life, 82% are sacrococcygeal. The head and neck region is the second most common location for teratomas in early infancy, accounting for five (14%) of those cases. We describe a female neonate with a terat...

PURPOSE The surgical treatment of urogenital sinus anomalies has undergone significant advances in recent years. Total urogenital mobilization, which mobilizes the urogenital sinus, vagina and urethra en bloc toward the perineum, represents one of these advances. MATERIALS AND METHODS We have improved our results with total urogenital mobilization by incorporating the mobilized urogenital sin...

A series of human germ cell-derived tumors were examined for the presence of nucleoli which persist through mitosis. Embryonal carcinomas, seminomas, and the cytotrophoblasts of choriocarcinomas had persistent nucleoli in more than 70% of mitoses. The differentiated cells derived from embryonal carcinomas, endodermal sinus tumors, and the more differentiated elements of choriocarcinomas only ra...