Background & aim: Pap smear is a screening procedure for cervical cancer. The incidence and mortality rate of cervical cancer has decreased up to 90% in the regular screening in women aged 20-65 years. This study aimed to investigate the Pap smear reports of pathology laboratories in Ahvaz, Iran. Methods: In this cross-sectional study, 1,006 Pap smear reports were collected from pathology labor...

CONTEXT More than half of the women diagnosed as having cervical cancer in the United States have not been screened within the last 3 years, despite many having had contact with the health care system. In many other regions of the world, there is only limited access to cervical cancer screening. OBJECTIVE To determine whether testing of self-collected vaginal swabs for human papillomavirus (H...

BACKGROUND Vaginal atrophy is a common complication in menopause which does not improve with time and, if untreated, can affect the quality of life for women. The aim of this study was to compare the effectiveness of the vaginal cream of hyaluronic acid and conjugated estrogen (Premarin) in treatment of vaginal atrophy. METHODS This study was a randomized controlled clinical trial on 56 menop...

The objective of this study was to determine the effect of medroxyprogesterone acetate (DMPA) on the development and maintenance of Candida albicans in the vagina of oophorectomized Wistar rats. The animals were divided into negative control groups (NCG), which received injections of sterile saline; positive control groups (PCG), which were given injections of estradiol valerate; and progestero...

In previous studies, permeability was shown to be one of the most important factors influencing the delivery of vidarabine and its 5’-O-esters in the vaginal membrane of the mouse. The present report describes the results of the extension of these studies to the guinea pig vaginal membrane. By a vaginal smear procedure, the estrous cycle (approx. 16 days in duration) was monitored by dividing i...

OBJECTIVES To determine whether intravaginal clindamycin cream reduces the incidence of abnormal pregnancy outcome in women with abnormal vaginal microbial flora graded as intermediate or BV and to investigate the effect of the antibiotic on vaginal microbial flora. METHODS A prospective cohort study of pregnant women in an antenatal clinic of a district general hospital. The subjects were 26...

BACKGROUND A screening programme for cervical cancer has been implemented in South Africa (SA) with intervals of 10 years after a normal cytological result. There are no studies that evaluate repeat screening at a shorter interval in SA. OBJECTIVES (i) To find the incidence of cytological abnormalities on a repeat test after a report of normal cytology or an inadequate Pap smear; and (ii) to ...

OBJECTIVE Non-specific cervicitis or inflammatory changes in a smear report are common which are usually unclear for clinical approaches. To investigate the frequency of inflammation and pathogenic vaginal microorganisms in cervical smears among an Iranian population sample. MATERIALS AND METHODS This cross-sectional study was carried out on Pap smear samples of women referred to gynecologica...

Background and aim: Pemphigus vulgaris (PV) is an autoimmune blistering disease which is known to involve the female genital tract but the frequency at which this occurs is unknown. There are relatively few reports in the literature of the cytological appearance of PV on cervicovaginal smears. Our aim was to evaluate involvement of the female genital tract and cervicovaginal Papanicolaou ...