PLATE 74. It has been shown by one of us (I) that the normal production of impulses in the region of the sino-auricular node is inhibited by stimulation of the right vagus nerve to a greater extent than by stimulation of the left. Earlier observations, which are fully discussed in that paper, had indeed indicated that such might prove to be the case ; but a clear demonstration of the prepondera...

The canine cervical trachea has been used for numerous studies regarding the neural control of tracheal smooth muscle. The purpose of the present study was to determine whether there is lateral dominance by either the left or right vagal innervation of the canine cervical trachea. In anesthetized dogs, pressure in the cuff of the endotracheal tube was used as an index of smooth muscle tone in t...

INTRODUCTION Many studies have demonstrated the existence of an anti-inflammatory, parasympathetic pathway, termed as the inflammatory reflex. Burn-induced heart failure has been investigated in many previous studies. Proinflammatory cytokines, such as TNF-alpha, IL-1beta, and IL-6, have been shown to play a key pathogenetic role and vagus nerve stimulation attenuates proinflammatory cytokine p...

739-742* =959* -The cardiac effects obtained by the stimulation of the vagus nerve were studied in the isolated heart preparation of cats, perfused with Tyrode’s solution according to Langendorff’s technique. High cervical stimulation of the vagus produced slight or no positive inotropic and chronotropic effects in the atropiniied heart. Excitation of the thoracic portion produced intense cardi...

Sympathetic activity and spatial dispersion of repolarization (DOR) have been implicated as mechanisms that promote arrhythmia vulnerability; yet there are no direct measurements of the effects of autonomic nerve stimulation on DOR. Rabbit hearts were perfused in a Langendorff apparatus with full sympathetic and parasympathetic innervation and were optically mapped to measure action potential d...