Fibromuscular dysplasia (FMD) is a non-atherosclerotic vascular disease that may involve medium-sized muscular arteries throughout the body. The pathogenesis of FMD remains poorly understood, but combination genetic and environmental factors be involved. majority patients are women, men have more progressive disease, especially when smoking. Besides classical phenotype string beads or focal ste...

Vascular liver disorders (VLDs) comprise a wide spectrum of clinical-pathological entities that primarily affect the hepatic vascular system both cirrhotic and non-cirrhotic patients. VLDs more frequently involve portal veins, as well sinusoids, resulting in an imbalance homeostasis with serious consequences, such development hypertension fibrosis. Surprisingly, many are characterized by prothr...

Diffuse systemic sclerosis (SSc) is a chronic disease of unknown cause characterized by diffuse fibrosis and vascular abnormalities in the skin and internal organs. Pathogenesis of SSc involves immunologic mechanisms, vascular damage and activation of fibroblasts. SSc varies in severity and progression; most patients eventually develop visceral complications, which are the usual causes of death...

the role of helicobacter pylori in development of gastric cancer

the adipokines, leptin and adiponectin, have a prominent role in the pathogenesis of coronary artery disease (cad). the inflammatory enzyme, myeloperoxidase (mpo) also has an important role in the pathogenesis of cad. association of the adipokines with mpo remains to be resolved in patients with cad. in this case-control study, 100 patients with cad and 100 control subjects were appropriately r...