Objective: To determine the efficacy of antitissue transglutaminase antibodies in diagnosis celiac disease children. Study Design: Observational Study. Setting: Department Peadiatric at Indus Medical College Hospital Tando Muhammad Khan. Period: July 2020 to December 2020. Material & Methods: Thirty five (35) cases were diagnosed be suffering from out 50. The mean age time was 6.67 years wi...

Celiac disease, a permanent, irreversible but treatable disease is an autoimmune triggered by gluten ingestion in genetically predisposed individuals, also known as celiac sprue and sensitive enteropathy. Recent findingsIntestinal inflammation villous atrophy small intestines permanent intolerance to disesea leads seveare malabsorption. About 20%-38% patients were basically nutritionally imbala...

A 48 year old female patient with intestinal malabsorption and subtotal to total jejunal villous atrophy also had granulomatous inflammation characterised by numerous epitheloid and giant cell granulomas in the stomach, the jejunum, and the liver, On a gluten-free diet a complete remission was achieved that included disappearance of the granulomatous inflammation. It is suggested that the granu...

November 01, 2008 Celiac disease (sprue) is a gluten-sensitive enteropathy of the gastrointestinal tract that affects the small intestine in individuals who are genetically susceptible. It is characterized by small intestinal malabsorption after the ingestion of gluten, villous atrophy of the small intestinal mucosa with increased intraepithelial lymphocytes, clinical and histologic improvement...

Capsule endoscopy (CE) has been increasingly used for diagnosing disease of the small bowel. It is an attractive technique for assessing celiac disease (CD) because it is noninvasive and provides a close and magnified view of the mucosa of the entire small bowel. The aim of this paper is to update the current data on the use of CE for diagnosing villous atrophy and complications of CD.

Intestinal changes, mainly in the jejunum, were investigated in 13 cases of malignant histiocytosis at necropsy and who had presented as lethal midline granuloma. Villous atrophy with crypt hyperplasia was observed in all cases, and a proliferation of atypical histiocytes was observed in seven cases. In the remaining cases, histiocytes with normal morphology increased in number. These findings ...