The extracellular matrix (ECM) is a complex assembly of structural proteins that provides physical support and biochemical signaling to cells in tissues. The mechanical properties of the ECM have been found to play a key role in regulating cell behaviors such as differentiation and malignancy. Gels formed from ECM protein biopolymers such as collagen or fibrin are commonly used for 3D cell cult...

Ligament viscoelasticity is an important determinant of tissue response to loading, and viscous dissipation modulates the potential for ligament damage or catastrophic failure. The nature of ligament viscoelastic response represents a combined measure of solid phase viscoelasticity and fluid movement. Both of these contributors are likely direction-dependent due to ligament anisotropy. Small si...

OBJECTIVES This study investigates the effect of aging on the radial viscoelastic behavior of the left ventricle (LV) based on a previously validated model that uses myocardial tissue phase mapping (TPM) of cine phase-contrast MRI. METHODS Previous studies suggest that aging remarkably influences regional myocardial motion, mostly myocardial velocities in both radial and long-axis directions....

The measurement of viscoelasticity of cells in physiological environments with high spatio-temporal resolution is a key goal in cell mechanobiology. Traditionally only the elastic properties have been measured from quasi-static force-distance curves using the atomic force microscope (AFM). Recently, dynamic AFM-based methods have been proposed to map the local in vitro viscoelastic properties o...

Surface tension and dilational viscoelasticity of solutions of various surfactants measured with bubble and drop profile analysis tensiometry are discussed. The study also includes experiments on the co-adsorption of surfactant molecules from a solution drop and alkane molecules from saturated alkane vapor phase. Using experimental data for 12 surfactants with different surface activities, it i...

A recently published finite element (FE) head model is modified to consider the viscoelasticity of the meninges, the spongy and compact bone in the skull. The cerebrospinal fluid (CSF) is simulated explicitly as a hydrostatic fluid by using a surface-based fluid modelling method, which allows fluid and structure interaction. It is found that the modified model yields smoother pressure responses...

We study control problems for some integro-differential equations using the Hilbert Uniqueness Method. To do that we follow a harmonic analysis approach. Our results can be applied to concrete examples in viscoelasticity theory.