نتایج جستجو برای: vismodegib
تعداد نتایج: 334 فیلتر نتایج به سال:
Journal:
:JAMA Dermatology
2015
Journal:
:American Journal of Gastroenterology
2020
Journal:
:Journal of Experimental Pharmacology
2012
Journal:
:New England Journal of Medicine
2012
Journal:
:Skin
2023
Journal:
:Journal of Clinical Pathology
2020
Journal:
:Journal of Cancer Therapy
2014
Journal:
:JAMA Dermatology
2015
2013
Hui Li
Natalie Lui
Tiffany Cheng
Hsin-Hui K. Tseng
Dongsheng Yue
Etienne Giroux-Leprieur
Hanh T. Do
Qing Sheng
Joy Q. Jin
Thomas W. Luh
David M. Jablons
Biao He
Malignant pleural mesothelioma (MPM) is a highly aggressive tumor with poor prognosis. Current treatment is rarely curative, thus novel meaningful therapies are urgently needed. Inhibition of Hedgehog (Hh) signaling at the cell membrane level in several cancers has shown anti-cancer activity in recent clinical studies. Evidence of Hh-independent Gli activation suggests Gli as a more potent ther...
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