Voxel-based analyses of tissue characteristics such as volume and T2 are usually carried out in isolation. However, as the images are analysed in a common voxel-based framework, it is possible to directly assess the spatial relationships of abnormalities detected by each technique. We utilize this approach in well-characterized patients with unilateral temporal lobe epilepsy (TLE) with hippocam...

K. S. Opstad, C. Ladroue, J. R. Griffiths, F. A. Howe Cancer Research UK Biomedical Magnetic Resonance Research Group, St. George's Hospital Medical School, London, United Kingdom Introduction In this study we investigated the use of pattern recognition techniques, using leave-one-out linear discriminant analysis (LDA) of single voxel H MRS, to distinguish metastases from glioblastomas; so far ...

Water column imaging multibeam echo sounder systems (MBESs) are a promising technology for quantitative estimates of the gas bubble volume flow within large seepage areas. Considerable progress has been made in recent years toward applicable calibration methods MBESs as well developing inversion models to convert acoustically measured backscattering cross sections flow. However, still not commo...

The introduction of multi-voxel pattern analysis (MVPA) to the functional magnetic resonance imaging (fMRI) community has brought a deeper appreciation for the diverse forms of information that can be present within fMRI activity. The conclusions drawn from MVPA investigations are frequently influenced by both the ability to decode information from multi-voxel patterns and mean activation level...

The amygdala has been considered to be essential for recognizing fear in other people's facial expressions. Recent studies shed doubt on this interpretation. Here we used movies of facial expressions instead of static photographs to investigate the putative fear selectivity of the amygdala using fMRI under more ecological conditions. The amygdala was found to respond more to movies of facial ex...

Accurate perception of the actions and intentions of other people is essential for successful interactions in a social environment. Several cortical areas that support this process respond selectively in fMRI to static and dynamic displays of human bodies and faces. Here we apply pattern-analysis techniques to arrive at a new understanding of the neural response to biological motion. Functional...