Platelet contractile forces play a major role in clot retraction and help to hold hemostatic clots against the vessel wall. Platelet forces are produced by its cytoskeleton, which is composed of actin and nonmuscle myosin filaments. In this work, we studied the role of Rho kinase, myosin light-chain kinase, and myosin in the generation of contractile forces by using pharmacological inhibitors a...

A physically based fault conceptual model is presented for modeling multiphase flow and transport processes in fractured rock of fault zones. In particular, we discuss a general mathematical framework model for dealing with fracture-matrix interactions, which is applicable to both continuum and discrete fracture conceptualization in fault zones. In this conceptual model, faults or fault zones o...

Repair of traumatic abdominal wall hernia (TAWH) has been reported to be necessary. Reported here is one case of TAWH without repair. A 27-year-old man was accidentally sandwiched between a rock and a truck and admitted to our emergency department. There was a swelling of 10 cm in the right upper quadrant of the abdomen. The enhanced computed tomographic scan demonstrated a large abdominal wall...

Ensuring the stability and integrity of underground gas storage salt caverns is a very complicated subject due to the non-linear and time-dependent behavior of rock salts under complicated thermal and mechanical loading conditions. For this reason, pressure and temperature fluctuations in the caverns and their surrounding strata must be integrated into the analysis and the numerical tools that ...

Once segmentation of 3D surface data of a rock pile has been performed, the next task is to determine the visibility of the surface rocks. A region boundary-following algorithm that accommodates irregularly spaced 3D coordinate data is presented for determining this visibility. We examine 3D surface segmentations of laboratory rock piles and determine which regions in the segmentation correspon...

To clarify the factors affecting stability of deep-buried hydraulic tunnels containing pore water, elastoplastic theory and Mogi-Coulomb strength criterion were used to derive analytical solutions stress on surrounding rock-lining structure, tunnel wall displacement, plastic zone radius in rock under different operating conditions. During this process, seepage effect interaction considered. The...

Rock fall related accidents continue to occur in coal mines, although artificial support mechanisms have been used extensively [1]. Roof stability is primarily determined in many underground mines by a limited number of methods that often resort to subjective criteria. It is argued in this paper that stability conditions of mine roof strata, as a key factor in coal mines, must be determined by ...