Perforated semiconductor neutron detectors are compact diode detectors that operate at low power and can be fashioned to have high thermal neutron detection efficiency. Fabricated from high-purity Si wafers, the perforations are etched into the diode surface with ICP-RIE and backfilled with LiF neutron reactive material. The intrinsic thermal neutron detection efficiency depends upon many facto...

BACKGROUND Clostridium difficile is a recognised cause of typhlocolitis and diarrhoea in neonatal pigs but has never been confirmed in association with pathology and disease in Irish pigs. CASE PRESENTATION Four neonatal piglets, with a history of diarrhoea were referred to the Central Veterinary Research Laboratory, Backweston for necropsy. They were from a fully integrated, commercial pig f...

Clostridium difficile is a global health burden and the leading cause of antibiotic-associated diarrhoea worldwide, causing severe gastrointestinal disease and death. Three well characterised toxins are encoded by this bacterium in two genetic loci, specifically, TcdB (toxin B) and TcdA (toxin A) in the Pathogenicity Locus (PaLoc) and binary toxin (CDT) in the genomically distinct CDT locus (Cd...

Context-aware services platforms aim at supporting the handling of contextual information in order to provide better user-tailored services. This paper proposes a novel services platform architecture to support mobile context-aware applications, giving emphasis to the configurability of the platform’s generic functionality. The paper introduces concepts and a language to cope with configurabili...

The yeast MAPKKK Ste11 activates three MAP kinase pathways, including pheromone signaling, osmosensing, and pseudohyphal/invasive growth pathways. We identified two chemical compounds, BTB03006 and GK03225, that suppress growth defects induced by Ste11 activation in diploid yeast cells. BTB03006, but not GK03225, was found to suppress growth defects induced by both alpha-factor and Ste4 G(beta)...

We analyze the physical conditions of the outflow seen in QSO 2359–1241 (NVSS J235953-124148), based on high resolution spectroscopic VLT observations. This object was previously studied using Keck/HIRES data. The main improvement over the HIRES results is our ability to accurately determine the number density of the outflow. For the major absorption component, level population from five differ...

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holoprosencephaly is a rare congenital brain malformation resulting from failure of diverticulation and cleavage of primitive prosencephalon which occurs at 4 - 8th week of gestation and is usually associated with multiple midline facial anomalies. it is the most common forebrain developmental anomaly in humans with prevalence of 1/16,000 in live borns, an incidence as high as 1:250 in conceptu...