enhanced immune cell trafficking into the central nervous system (cns) and disruption of the blood brain barrier are pathophysiological hallmarks of neuroinflammatory disorders like multiple sclerosis (ms) and its animal model, experimental autoimmune encephalomyelitis (eae). however, recent studies suggest that the coagulation and the contact-kinin system might also be involved in ms developme...

Background & Aims of the Study: Birth weight is one of the most fundamental and common health indicators used to assess the infants' status in each country. Maternal blood and its various cell types and parameters are of vital factors have impression on the fetus. Several risk factors are considered as the causes of low birth weight; however, in many cases it has no obvious reason. Thi...

Background & Aims of the Study: Birth weight is one of the most fundamental and common health indicators used to assess the infants' status in each country. Maternal blood and its various cell types and parameters are of vital factors have impression on the fetus. Several risk factors are considered as the causes of low birth weight; however, in many cases it has no obvious reason. This study a...

Increase of blood glucose level In pregnant woman correlated with increased risk maternal morbidity, and problems in labour also affect child outcome. This phenomena cause by physiological changes occur pregnancy such as placental factor inflammation circulation. Changes like tumor nerosis (TNF-α) beta-cell gene disfunction (potassium voltage-gated channel KQT-like 1 (Kcnq1) glucokinase (Gck)) ...

  Stem cells are undifferentiated self regenerating multi potential cells. There are three types of stem cells categories by the ability to form after cells and correlated with the body’s development process. Totipotent: these stem cells can form an entire organism such as fertilized egg. Ploripotent: ploripotent cells are those that can form any cell in the body but cannot form an entire organ...

background: lead toxicity has been reported to affect hematopoietic, nervous, reproductive, cardiovascular and urinary tract systems. many investigators have so far studied the effects of high blood lead levels on pregnancy outcomes. objective: to investigate the effects of elevated maternal blood lead during pregnancy on some trace elements and pregnancy outcomes. methods: blood lead and plasm...

in this study, we investigate the immunostimulatory effects of alcoholic extract of the coffee seed on cell-mediated immune response andcyclophosphamide-induced (cp) immunosuppressed mice. the assessment of cellular immune function was carried out by the measurement of delayed-type hypersensitivity (dth) response. according to the literature survey, cyclophosphamide has only suppressing effect ...

a hybridoma clone designated 6g5 has been selected by fusion of mouse myeloma cell line ag. 8653 with spleen cells from mice immunized with human peripheral blood mononuclear cells (pbmc). the antibody produced by this clone was found to be strongly reactive with four human b-cell lines in the conventional immunological assays. despite the fact that expression of most b cell-associated markers ...