This study determines whether changes in abdominal (ABD) and gluteal (GLT) adipose tissue lipoprotein lipase (LPL) activity in response to a 6-mo weight loss intervention, comprised of a hypocaloric diet and low-intensity walking, affect changes in body composition, fat distribution, lipid metabolism, and the magnitude of weight regain in 36 obese postmenopausal women. Average adipose tissue LP...

INTRODUCTION Due to the increased number of bariatric surgeries over the years, aspects contributing or hindering the achievement of outcomes, among them weight regain, have acquired increased significance. Psychological factors directly influence on this unwanted situation, but there are few studies and controversies about the degree of participation of these factors. We propose a qualitative ...

Although weight loss can usually be achieved by restricting food intake, the majority of dieters regain weight over the long-term. In the hypothalamus, hormonal signals from the gastrointestinal tract, adipose tissue and other peripheral sites are integrated to influence appetite and energy expenditure. Diet-induced weight loss is accompanied by several physiological changes which encourage wei...

OBJECTIVE We tested genetic associations with weight loss and weight regain in the Diabetes Prevention Program, a randomized controlled trial of weight loss-inducing interventions (lifestyle and metformin) versus placebo. RESEARCH DESIGN AND METHODS Sixteen obesity-predisposing single nucleotide polymorphisms (SNPs) were tested for association with short-term (baseline to 6 months) and long-t...

Background: Approximately 25% of patients after bariatric surgery either do not lose enough weight or regain a considerable amount weight, both are referred to as nonresponse. This study aimed t...

Weight gain is common among postobese individuals, providing an opportunity to address the cost of weight regain on energy expenditure. We investigated the energy cost of weight regain over 1 yr in 28 women [age 39.5 +/- 1.3 (SE) yr; body mass index 24.2 +/- 0.5 kg/m(2)] with recent weight loss (>12 kg). Body composition, total energy expenditure (TEE) using doubly labeled water, resting metabo...

OBJECTIVE To investigate the relationship between binge eating behavior and weight loss maintenance over a two-year period in adults. DESIGN Secondary data analysis using the Keep It Off study, a randomized trial evaluating an intervention to promote weight loss maintenance. PARTICIPANTS 419 men and women (ages: 20 to 70 y; BMI: 20-44 kg/m2) who had intentionally lost ≥10% of their weight d...

• To introduce health and fitness professionals to the role of low energy dense diets as a method of promoting healthy weight loss and eating behaviors and the prevention of weight regain. Currently, 68% of the U.S. population is estimated to be overweight or obese. Many of these individuals struggle at weight loss and the prevention of weight regain once weight has been lost. Learning to follo...

BACKGROUND Conjugated linoleic acid (CLA) is marketed as a safe, simple, and effective dietary supplement to promote the loss of body fat and weight. However, most previous studies have been of short duration and inconclusive, and some recent studies have questioned the safety of long-term supplementation with CLA. OBJECTIVE Our aim was to assess the effect of 1-y supplementation with CLA (3....

BACKGROUND A recently published prospective series has demonstrated that weight loss ceases 18 to 24 months following Laparoscopic Roux-en-Y gastric bypass (RYGB) and that, by 48 months, there is significant weight regain in 50% of patients. METHODS We report the case of a 38-year-old male patient who developed significant weight regain 42 months following laparoscopic (RYGB) and underwent la...