One of the mechanisms through which regular exercise contributes to weight maintenance could be by reducing intake and preference for high-fat (HF) diets. Indeed, we previously demonstrated that wheel-running rats robustly reduced HF diet intake and preference. The reduced HF diet preference by wheel running can be so profound that the rats consumed only the chow diet and completely avoided the...

BACKGROUND Chronic fatigue stress (CFS) is an important health problem with unknown causes and unsatisfactory prevention strategies, often characterized by long-lasting and debilitating fatigue, myalgia, impairment of neuro-cognitive functions along with other common symptoms. The present study has been designed to explore the protective effect of statins against running wheel activity induced ...

Voluntary wheel running can potentially be used to exacerbate the disease phenotype in dystrophin-deficient mdx mice. While it has been established that voluntary wheel running is highly variable between individuals, the key parameters of wheel running that impact the most on muscle pathology have not been examined in detail. We conducted a 2-week test of voluntary wheel running by mdx mice and...

This paper presents a wheel–terrain interaction model, which enables efficient modeling of wheeled locomotion in soft soil and numerical simulations of off-road mobile robots. This modular model is derived based on wheel kinematics and terramechanics and the main focus is on describing the stress distributions along the wheel–terrain interface and the reaction forces exerted on the wheel by the...

Background: The purpose of this study was to examine the effects of voluntary wheel running on the positive reinforcing effects of heroin in rats with an established history of drug self-administration. Methods: Rats were assigned to sedentary (no wheel) and exercise (wheel) conditions and trained to self-administer cocaine under positive reinforcement contingencies. Rats acquiring cocaine self...

BACKGROUND The purpose of this study was to examine the effects of voluntary wheel running on the positive reinforcing effects of heroin in rats with an established history of drug self-administration. METHODS Rats were assigned to sedentary (no wheel) and exercise (wheel) conditions and trained to self-administer cocaine under positive reinforcement contingencies. Rats acquiring cocaine self...

wheel-set is an important part of EMU. It directly influences the EMU operation security. In recent years, some harmful circumferential and radial defects are found in the wheel rim, which occur between the periods of two light maintenances. The comprehensive security system of wheel-set has already built in china to guarantee the EMU maintenance quality and operation security. It consists of r...

An Ackerman steering linkage for short wheelbase, four-wheel vehicles has been developed. The linkage coordinates the steering angle of each wheel through a range of 180 degrees with minimal misalignment between wheels. Control of steering angles is accomplished using a single linear actuator. Control complexity is lower compared to four-wheel systems using individually controlled steering actu...

A uni-stroke text input strategy for wheel input controls is proposed, such as the wheel controls found on the 5th generation ipod multimedia devices. The popularity of the ipod indicates that the wheel input paradigm is intuitive and usable. The proposed uni-strokes are based on circular motions that follow the contour of the wheel. Spatial mnemonics based on the shape of the alphabetic charac...

The purpose of this review is to highlight the wide array of interfaces developed so far to control wheel chairs. A preliminary study on wheel chair interfaces is presented. This is followed by various types of powered wheel chair control methods such as hand, voice, communication methods and hybrid. Wheel chair control methods for persons with reduced strength are also explained. Apart from al...