In museums, it is critical to properly conserve the existing artwork. For this purpose, it is fundamental to continuously monitor its environment, either in storage or exhibition rooms. Contrarily to traditional measuring equipments and procedures used in museums, the deployment of a Wireless Sensor Network (WSN) can help to implement these measurements continuously, in a real-time basis, and i...

The approach of controlling the false discovery rate (FDR) which is less conservative than controlling the family wise error rate (FWER) has become a new and popular multiple testing procedure in microarray studies. In addition to multiple testing problems the limitation of sample size is another big challenge in this area. This thesis addresses the problem of multiple testing in the context of...

Genetic association tests involving copy-number variants (CNVs) are complicated by the fact that CNVs span multiple markers at which measurements are taken. The power of an association test at a single marker is typically low, and it is desirable to pool information across the markers spanned by the CNV. However, CNV boundaries are not known in advance, and the best way to proceed with this poo...

OBJECTIVES Discussion of different error concepts relevant to microarray experiments. Review of some commonly used multiple testing procedures. Comparison of different approaches as applied to gene expression data. METHODS This article focuses on familywise error rate (FWER) and false discovery rate (FDR) controlling procedures. Methods under investigation include: Bonferroni-type methods and...

In the filtrates of typhus-infected tissues of guinea pigs can be occasionally found a substance which produces in these animals thermic reactions, lesions characteristic of experimental typhus, and, still less frequently, inimunity to later injections of active virus. The general indications are that this substance is not a living organism.

BACKGROUND In recent years, analyses of event related potentials/fields have moved from the selection of a few components and peaks to a mass-univariate approach in which the whole data space is analyzed. Such extensive testing increases the number of false positives and correction for multiple comparisons is needed. METHOD Here we review all cluster-based correction for multiple comparison m...

BACKGROUND Testing for clustering at multiple ranges within a single dataset is a common practice in spatial epidemiology. It is not documented whether this approach has an impact on the type 1 error rate. METHODS We estimated the family-wise error rate (FWE) for the difference in Ripley's K functions test, when testing at an increasing number of ranges at an alpha-level of 0.05. Case and con...

A juxta-apikális radiolucencia (JAR) egy olyan radiológiai jel, amely jól körülhatárolt radiolucens területként jelenik meg az alsó bölcsességfogak apikális és laterális felszínén. Egyes vizsgálatok alapján a JAR jelenléte közvetlen összefüggésbe hozható bölcsességfog eltávolítása során bekövetkező nervus alveolaris inferior sérüléssel, míg más vizsgálatokban ezt nem bizonyították. Jelen tanulm...

The Jazz file format is intended to be a replacement for the JAR file format when used for storage and distribution of Java programs. A Jazz file is compressed to a degree that far exceeds what is possible with a JAR file. The smaller size of the Jazz format permits faster transmission speeds over a network and has the additional benefit of conserving disk storage. The compression is achieved a...