Disease heterogeneity remains a major challenge for the understanding of systemic lupus erythematosus (SLE). Recent work has revealed the important role of nonimmune factors in the development of end-organ damage involvement, shifting the current paradigm that views SLE as a disease inflicted by a disturbed immune system on passive target organs. Here, we discuss the pathogenesis of lupus nephr...

OBJECTIVE The present study was designed to verify if mini-implant prototypes (MIP) developed for Herbst appliance anchorage are capable of withstanding orthopedic forces, and to determine whether the flexural strength of these MIP varies depending on the site of insertion (maxilla and mandible). METHODS Thirteen MIP were inserted in three minipig cadavers (six in the maxilla and seven in the...

The paper considers the possibility of reusing previously used railway rails. analysis is conducted using standards and operating conditions rails one Central Asian states, Kazakhstan, as an example. operation these causes significant stresses, while surface layers are strengthened a result cold hammering. These phenomena significantly change physical mechanical characteristics As result, they ...

This study aims to assess the efficiency of National Economic Recovery (PEN) program budget launched by government reduce impact pandemic on public welfare in 34 provinces Indonesia. Efficiency measurements computed using Data Envelopment Analysis (DEA) show that only 12 are efficient at holding increase poverty and unemployment implementing PEN budget. West Papua Province is despite its levels...

Ukraine defied expectations by withstanding a full-scale Russian invasion in 2022, demonstrating the resilience of both local and national institutions. This was striking contrast with 2014, when Russia seized Crimea backed separatist revolts east Ukraine, Ukrainian response had been weak divided. Since then, has strengthened its institutions building political legitimacy capacity armed forces,...

The existing quicksands in the desert are among problematic soils whose stabilization has been considered by experts. Emulsion bitumen is one of environmentally friendly stabilizers these sands. Also, method reinforcement with (fibers) many advantages due to increase soilstrength same way and formation thickness soil mass. aim this study was investigate effect polypropylene fibers emulsion on i...

Regenerative hydrogen/vanadium flow cells (RHVFCs) require electrode architectures combining electrochemical, catalytic, and mechanical properties across nano-, micro-, milliscales. The use of current carbon-based electrodes can lead to poor electrolyte utilization, slow kinetics, rapid deterioration, resulting in suboptimal electrochemical performance hindering RHVFC’s commercial viability. To...

Vacuum-dielectric interface is the most vulnerable part of vacuum insulation systems where surface electrical breakdown prone to happen, hence severely restricts development advanced electro-vacuum devices with large capacity and its miniaturisation. Generally, a direct effective way improve alleviate initiation multipactor phenomena. Inspired by this approach, authors report 3D-printed structu...

Biobanks have been heralded as essential tools for translating biomedical research into practice, driving precision medicine to improve pathways for global healthcare treatment and services. Many nations have established specific governance systems to facilitate research and to address the complex ethical, legal and social challenges that they present, but this has not lead to uniformity across...