OBJECTIVE To compare the responsiveness of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and a questionnaire format of the Lequesne-Algofunctional Index in patients with OA of the lower extremities. METHODS Longitudinal analysis of the instruments' responsiveness [standardized response mean (SRM), effect size (ES)] in ambulatory patients undergoing hip or knee art...

OBJECTIVE To correlate muscule performance, body composition, pain and joint function in elderly people with gonarthrosis. METHOD 21 elderly patients were submitted to bioelectrical impedance analysis, dynamometry associated with electromyographic (EMG) evaluation of isometric knee extension, in addition to pain assessment by the Numeric Pain Intensity Scale and function assessment, by the We...

Introduction:Knee osteoarthritis (KOA), one of the most common articular diseases, sometimes leads to severe disability. This study aimed to estimate the prevalence of knee-buckling in patients with KOA during the past three months and to investigate its relation with the physical function. Methods:A cross-sectional study was performed on 190 patients with KOA...

Background Due to its major public health impact, knee osteoarthritis (KOA) has been designated as a serious disease by the US Food and Drug Administration (FDA). Approval of modifying drug (DMOAD) slow or prevent progression hinges on demonstrating both symptomatic (i.e., how patient feels functions) structural improvement. The Western Ontario McMaster Universities Osteoarthritis Index (WOMAC)...

BACKGROUND Traditionally, the results of revision total knee arthroplasty have been determined with use of surgeon-based measures such as the Knee Society rating system. Recently, outcome and quality-of-life measures have shifted toward a greater emphasis on patient-based evaluation. The aim of our study was to determine the validity and responsiveness of the Knee Society rating system compared...

BACKGROUND Specific growth factors have been proposed as therapeutic proteins for cartilage repair. HYPOTHESIS Platelet-rich plasma (PRP) provides symptomatic relief in early osteoarthritis (OA) of the knee. STUDY DESIGN Randomized controlled trial; Level of evidence, 1. METHODS A total of 78 patients (156 knees) with bilateral OA were divided randomly into 3 groups. Group A (52 knees) re...

OBJECTIVE The objective of this study was to establish the non-inferiority of an oral enzyme therapy (Phlogenzym-(PE)) as compared to the non-steroidal anti-inflammatory drug (NSAID) diclofenac (DC) in patients with osteoarthritis (OA) of the hip. METHODS Ninety patients presenting with painful episodes of OA of the hip were treated for 6 weeks in one study centre in a phase III, randomised, ...