The study was conducted at the University of Nebraska Pesticide Application and Technology Laboratory in North Platte, July 2015. Two application volume rates (100 200 l · ha−) three nozzle types (XR, AIXR, TTI) were selected two flow (0.8 1.6 min−) a single speed 7.7 km h−. Each collector type [Mylar washed (MW), Mylar image analysis (MIA), water-sensitive paper (WSP), Kromekote (KK)] arranged...

OBJECTIVE Delayed-release metformin (Met DR) is formulated to deliver the drug to the lower bowel to leverage the gut-based mechanisms of metformin action with lower plasma exposure. Met DR was assessed in two studies. Study 1 compared the bioavailability of single daily doses of Met DR to currently available immediate-release metformin (Met IR) and extended-release metformin (Met XR) in otherw...

INTRODUCTION Magnetic resonance imaging (MRI) has been shown to be superior to radiography (XR) for assessing synovitis, osteitis, and bone erosion in rheumatoid arthritis (RA), particularly in clinical trials. However, relatively little has been reported on the ability of MRI to evaluate articular cartilage loss, or joint-space narrowing (JSN), in the hands and wrists. In a previous study, we ...

BACKGROUND Xylose reductase (XR) and xylitol dehydrogenase (XDH) from Pichia stipitis are the two enzymes most commonly used in recombinant Saccharomyces cerevisiae strains engineered for xylose utilization. The availability of NAD+ for XDH is limited during anaerobic xylose fermentation because of the preference of XR for NADPH. This in turn results in xylitol formation and reduced ethanol yie...

We report x-ray reflectivity ~XR! and small-angle off-specular diffuse-scattering ~DS! measurements from the surface of liquid indium close to its melting point of 156 °C. From the XR measurements we extract the surface structure factor convolved with fluctuations in the height of the liquid surface. We present a model to describe DS that takes into account the surface structure factor, thermal...

Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis. An extended-release (XR) formulation has been designed to provide a once-daily (QD) dosing option to patients to achieve comparable pharmacokinetic (PK) parameters to the twice-daily immediate-release (IR) formulation. We conducted 2 randomized, open-label, phase 1 studies in healthy volunteers. Study A cha...

Consider a finite number of variables Xn, n ∈ N, in the respective finite sets Xn. For R ⊆ N, we denote by XR the tuple of variables that takes values in the Cartesian product XR := ×r∈RXr. We denote by G (XR) the set of gambles on XR. Suppose DN ⊆ G (XN) models a subject’s beliefs about XN, Marginalisation. The corresponding beliefs about the variable XO, where O⊆ N, are given by the marginal ...

Extended reality (XR), here jointly referring to virtual, augmented, and mixed (VR, AR, MR) reality, is becoming more common in everyday working life. This paper presents a systematic literature review of academic publications on XR indicating changes practical organization work. We analyse both application areas theoretical methodological approaches research. The process followed the PRISMA st...

The inspiratory intercostal muscles elevate the ribs and thereby elicit a fall in pleural pressure (DeltaPpl) when they contract. In the present study, we initially tested the hypothesis that this DeltaPpl does, in turn, oppose the rib elevation. The cranial rib displacement (Xr) produced by selective activation of the parasternal intercostal muscle in the fourth interspace was measured in dogs...

Economical biofuel production from plant biomass requires the conversion of both cellulose and hemicellulose in the plant cell wall. The best industrial fermentation organism, the yeast Saccharomyces cerevisiae, has been developed to utilize xylose by heterologously expressing either a xylose reductase/xylitol dehydrogenase (XR/XDH) pathway or a xylose isomerase (XI) pathway. Although it has be...