Identification of spermatozoa is the biological evidence most often sought in the examination of rape victims. Absence of spermatozoa usually terminates biological investigations, and the victim’s testimony can therefore be contested. We assessed the utility and reliability of PCR amplification using Ychromosomal STR polymorphisms in specimens taken from female victims of sexual assault with ne...

AIM To evaluate the novel triplex polymerase chain reaction (PCR) assay for the analysis of polymorphic Y-chromosomal short tandem repeat loci (Y-STR). METHODS A total of 14 Y-STR loci was analyzed. Allele frequencies for 3 tetrameric Y-STR loci (DYS449, DYS456, and DYS458) and extended haplotype loci typed by Y-PLEXTM 12 system were investigated in a sample of 50 unrelated healthy Czech male...

The Y chromosome carries several genes involved in spermatogenesis, which are distributed in three regions in the euchromatic part of the long arm, called AZFa (azoospermia factor a), AZFb, and AZFc. Microdeletions in these regions have been seen in 10-15% of sterile males with azoospermia or severe oligozoospermia. The relatively high de novo occurrence of these microdeletion events might be d...

OBJECTIVE This study aims to evaluate associations between variations in genes involved in the metabolism of environmental chemicals and steroid hormones and risk of menopause in smokers. METHODS Survival analysis was performed on 410 eligible participants from the Penn Ovarian Aging study (ongoing for 14 years), a cohort study of late-reproductive-age women. Single nucleotide polymorphisms a...

results the frequencies of the aa, at, and tt genotypes were 31%, 51%, and 18% in the chronic hbv patient group, and 40%, 45%, and 15% in the healthy control group, respectively. however, a lack of association of the + 874 polymorphism in the ifn-γ gene of those with chronic hbv infection was found. evaluation of hbv association with this polymorphism was significant under the dominant genetic ...

background: clopidogrel is a standout amongst the most ordinarily recommended medications to avoid ischemic occasions taking after coronary disorder or stant position. however, impaired responses the therapy as well as resistance to the therapy have also been reported. genetic variants play an important role in clopidogrel biotransformation of its active metabolite that may subsequently influen...

results the allele and genotype distributions of pnpla3 rs738409 and rs2281135 were not significantly different between the chb and lc groups. after segregation on the basis of sex, no significant correlation between pnpla3 (rs738409 and rs2281135) genotypes/alleles and liver cirrhosis was detected. moreover, none of the haplotypes in pnpla3 (rs738409 and rs2281135) was found to be statisticall...

BACKGROUND Genetic predisposition to adiposity may interact with dietary protein in relation to changes of anthropometry. OBJECTIVE To investigate the interaction between genetic predisposition to higher body mass index (BMI), waist circumference (WC) or waist-hip ratio adjusted for BMI (WHRBMI) and dietary protein in relation to subsequent change in body weight (ΔBW) or change in WC (ΔWC). ...

the flowering and fructification period of the chilean strawberry (fragaria chiloensis (l.) duch.) is restricted to approximately 2 mo, which seriously limits the commercial development of the species. the objective of the current investigation was to identify inter simple sequence repeat (issr) polymorphisms associated with flowering duration in accessions of f. chiloensis. the flowering durat...

conclusions the results of this study indicate that the rs12979860 cc genotype of il28b was associated with a response to peg-ifnα-2a/rbv combination therapy in azerbaijani patients with hcv-1b infection. therefore, host genetics may be useful in predicting the response to hepatitis c treatment. objectives the aim of the current study was to determine the relationship between rs12979860 polymor...