In vitro insulinomimetic activities of Zn(II) complexes with three natural products, betaine, L-lactic acid, and D-(-)-quinic acid (qui), were found in rat adipocytes treated with epinephrine in terms of the inhibition of free fatty acid release. Based on the results, the blood glucose lowering effect in KK-A(y) mice with type 2 diabetes mellitus was observed by daily i.p. injections of a monom...

A simple, sensitive, reliable and flexible flow injection spectrophotometric method is proposed for on-line preconcentration and determination of trace amounts of zinc in water. At the presence of Tween-80 in pH 9.3 buffer solutions, the shade of color of Zn (II)-PAN complex is in a linear relation to the zinc amount at the point of the maximum absorption peak of 560 nm. The optimal experimenta...

In the title centrosymmetric dinuclear zinc(II) complex, [Zn(2)(C(36)H(42)N(4)O(2))(NO(3))(2)], the Zn(II) atom has a distorted octa-hedral geometry, defined by two N atoms and two O atoms from the macrocyclic ligand and two O atoms from a chelating nitrate anion and are bridged by two phenolate O atoms, forming a four-membered Zn(2)O(2) ring.

Metal binding strategies employing low molecular weight chelators and equilibrium dialysis were used to investigate several unresolved aspects of zinc and copper binding to serum albumin. Direct measurement of histidine binding to bovine serum albumin when the histidine is presented either as a metal-chelate or alone provides no evidence for an albumin-metal-histidine ternary complex. Using pre...

The title complex, [ZnBr(2)(C(11)H(17)N(3))], is a mononuclear zinc(II) compound derived from the Schiff base N-propyl-N'-(1-pyridin-2-ylmethyl-idene)ethane-1,2-diamine. The Zn(II) atom is five-coordinate, binding to the imine N, pyridine N, and amine N atoms of the Schiff base ligand and to two bromide anions in a distorted trigonal-bipyramidal coordination geometry. Adjacent mol-ecules are li...

A method was developed for the determination of zinc(II) dimethyldithiocarbamate by converting it into the copper(II) dithiocarbamate complex, which is then extracted into molten naphthalene. The absorbance is measured at 430 nm versus a reagent blank. Beer's law is obeyed for concentrations of 0.63 x 10(-3) to 17.2 x 10(-3) g/L in the final solution. The method is sensitive and was applied to ...

The title compound, [ZnCl(2)(C(12)H(16)BrClN(2)O)], is a mononuclear zinc(II) complex. The Zn(II) atom is four-coordinate in a tetra-hedral geometry, binding to the phenolate O and imine N atoms of the zwitterionic Schiff base ligand and to two Cl(-) ions. In the crystal structure, mol-ecules are linked through inter-molecular N-H⋯Cl hydrogen bonds to form chains running along the a axis.

a selective and sensitive method for determination of cadmium and zinc is presented. the method is based on adsorptive accumulation of the complexes of cd (ii) and zn (ii) ions with 4-amiono-5-methyl-2,4-dihydro-3h-1,2,4-triazol-3-tion (mmtt) onto hanging mercury drop electrode (hmde), followed by reduction of the adsorbed species by voltammetric scan using differential pulse modulation. the li...

In the title mononuclear zinc(II) complex, [ZnCl(2)(C(14)H(20)N(2)O)]·H(2)O, the Zn(II) atom is four-coordinated by the phenolate O and imine N atoms of the Schiff base ligand and by two Cl atoms in a tetra-hedral geometry. In the crystal structure, O-H⋯Cl, O-H⋯O and N-H⋯O hydrogen bonds involving the water mol-ecules bridge adjacent complexes into a ladder-like structure running along the c axis.

The Cu,Zn superoxide dismutases (Cu,Zn SOD) isolated from some Gram-negative bacteria possess a His-rich N-terminal metal binding extension. The N-terminal domain of Haemophilus ducreyi Cu,Zn SOD has been previously proposed to play a copper(II)-, and may be a zinc(II)-chaperoning role under metal ion starvation, and to behave as a temporary (low activity) superoxide dismutating center if coppe...