نتایج جستجو برای: α gene
تعداد نتایج: 1281484 فیلتر نتایج به سال:
Dystrophin, a gene product that is mutated in individuals with Duchenne muscular dystrophy, is tethered to the extracellular matrix via membrane-associated multimolecular complexes. In striated muscle cells this complex contains two glycoprotein subcomplexes, the sarcoglycan (SG) and dystroglycan (DG) complexes. Disruption of these large transmembrane complexes has been shown to result in muscl...
BACKGROUND This study was performed to evaluate association of gene polymorphisms among proinflammatory cytokines and susceptibility to chronic idiopathic urticaria (CIU). METHODS Ninety patients with prolonged urticaria more than 6 weeks were included as case group. Single nucleotide polymorphisms (SNPs) of IL-6 (G/C -174, G/A nt565) and TNF-α (G/A -308, G/A -238) were evaluated, using polym...
Tumor necrosis factor alpha (TNF-α) is a proinflammatory cytokine with an important role in the pathogenesis of several diseases. Its encoding gene is located in the short arm of chromosome 6 in the major histocompatibility complex class III region. Most of the TNF-α gene polymorphisms are located in its promoter region and they are thought to affect the susceptibility and/or severity of differ...
Nasopharyngeal swab collection for SARS-CoV-2 examination by RT-PCR requires Viral Transport Medium (VTM) using VTM non-activated and inactivated. This study determined the difference in CT values SARS CoV-2 inactivated VTM. is a comparative analytical with cross-sectional method 20 confirmed positive samples at RSU. Dr. Suyoto was analyzed T-Independent test (N gene) Mann-Whitney (ORF1ab SPSS ...
Objectives: (1) Obtain complete genomic clones plus promoter regions of apple peel genes encoding HMGR isozymes HMG2 and HMG3 and determine whether expression of these genes is regulated by ethylene; (2) Demonstrate function of the gene product and obtain a genomic clone of the ethyleneresponsive promoter of the putative apple α-Farnesene Synthase gene; (3) Determine correlation among ethylene-...
Background: Colorectal cancer (CRC) is one of the most common malignant tumors in world, which has been introduced as third and leading cause death. This uncommon before age 50. Its prognosis controversial, many studies report a poor older patients, others show no difference. In addition to factors, such diet, environmental somatic, hereditary mutations, genetic including altered expression som...
Alpha thalassemia is a genetic disease characterized by insufficient expression or definite absence of the α-globin chain. Three large deletions (thal-1; 26.5 kb MedII, 20.5 and 17.4 MedI) two small (thal-2; 4.2 3.7 kb) have been in our country. In addition, different PolyA mutations (PA1: AATAAA>AATAAG PA2: AATAAA>AATGA) on α2-globin gene (αα/αPAα), 5nt deletion (αα/α5ntα), unstable Hb v...
Little information on the effects of a high α-linolenic acid (C18:3n-3) diet fatty composition and lipid-producing gene expression in hepatopancreas from Yellow River carp (Cyprinus carpio). In study, 60 common juveniles were fed for 50 days, supplemented with linseed oil (LO), control without addition to evaluate effect lipid peroxisome proliferator-activated receptors (PPAR-α), delta-6 desatu...
TNF-α is an important human cytokine that imparts dualism in malaria pathogenicity. At high dosages, TNF-α is believed to provoke pathogenicity in cerebral malaria; while at lower dosages TNF-α is protective against severe human malaria. In order to understand the human TNF-α gene and to ascertain evolutionary aspects of its dualistic nature for malaria pathogenicity, we characterized this gene...
background: alpha thalassemia (α-thal) is one of the most common hemoglobinopathies worldwide. the aim of this study was to investigate the spectrum of α-thal mutations among premarital baluch couples in southeastern iran. subjects and methods: we assessed 1215 individuals by multiplex gap polymerase chain reaction (gap-pcr) and amplification refractory mutation system (arms-pcr). results: of t...
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