نتایج جستجو برای: β tubulin
تعداد نتایج: 187441 فیلتر نتایج به سال:
mesenchymal stem cells (mscs) have the ability to differentiate into neuronal like cells under appropriate culture condition. in this study, we investigated whether mscs derived from human peripheral blood (pb-mscs) can differentiate into neuronal like cells by synergic effect of the growth factors egf, bfgf and noggin. for this purpose, the expression of five neuronal markers (nestin, β iii tu...
Haemonchus contortus is one of the most important parasitic nematodes of small ruminants around the world, particularly in tropical and subtropical regions. The control of haemonchosis relies mainly on anthelmintics, but the excessive and prolonged use of anthelmintics is causing serious drug resistance issues in many countries. As benzimidazole (BZ) anthelmintics have been broadly used in Chin...
BACKGROUND Previous studies have shown ketamine can alter the proliferation and differentiation of neural stem cells (NSCs) in vitro. However, these effects have not been entirely clarified in vivo in the subventricular zone (SVZ) of neonatal rats. The present study was designed to investigate the effects of ketamine on the proliferation and differentiation of NSCs in the SVZ of neonatal rats i...
OBJECTIVE To investigate the role and mechanism of suppressor of cytokine signaling 1 (SOCS1) in the regulation and differentiation of C17.2 neural stem cells (NSCs). METHODS In this study, lentiviral (LV)-SOCS1-enhanced green fluorescent protein (EGFP) was constructed and transfected into C17.2 NSCs. There were three groups of C17.2 NSCs: LV-SOCS1-EGFP, LV-EGFP, and phosphate-buffered saline...
Botrytis aclada and allii, associated with onion gray-mold neck rot isolated in Hokkaido, were tested for sensitivity to benzimidazole. Of the B. strains, 59% highly resistant remaining 41% sensitive; all strains of allii sensitive. Resistant widespread Hokkaido. We analyzed sequences β-tubulin gene detected replacement glutamic acid (GAG) by lysine (AAG) at codon 198. This is first report benz...
Mutations in LRRK2, encoding the multifunctional protein leucine-rich repeat kinase 2 (LRRK2), are a common cause of Parkinson disease. LRRK2 has been suggested to influence the cytoskeleton as LRRK2 mutants reduce neurite outgrowth and cause an accumulation of hyperphosphorylated Tau. This might cause alterations in the dynamic instability of microtubules suggested to contribute to the pathoge...
Western Blot Membranes were immunoblotted with the following primary antibodies: rabbit polyclonal anti-Lmp7 (1:2000; AbD Serotec); rabbit polyclonal anti-β2M (1:1000; Proteintech); mouse anti β-actin (1:30000; Chemicon); mouse anti importin-β; (1:5000; Millipore); mouse anti-acetylated tubulin (1:1000; Millipore); mouse anti β-tubulin (1:1000; Millipore); rabbit anti-ERK (K23, 1:1000; Santa Cr...
Microtubules are hollow rod-like polymers (figure 1). They fulfill a varied range of functions including maintenance of cell integrity, forming a spindle that facilitates chromosome separation and as a protein polymer ‘track’ for intracellular transport by molecular motors such as kinesin and dynein. Each microtubule is made of 13 protofilaments consisting of linearly arranged tubulin molecules...
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