We present spectroscopic and extensive photometric observations of supernova (SN) 1998de in the S0 galaxy NGC 252, discovered during the course of the Lick Observatory Supernova Search. These data, which span a time period of 8 days before to 76 days after B-band maximum, unambiguously establish SN 1998de as a peculiar and subluminous type Ia supernova (SN Ia) with strong similarities to SN 199...

Supernova (SN) rates are a potentially powerful diagnostic of star formation history (SFH), metal enrichment, and SN physics, particularly in galaxy clusters with their deep, metal-retaining potentials and simple SFH. However, a low-redshift cluster SN rate has never been published. We derive the SN rate in galaxy clusters at 0:06 < z < 0:19, based on Type Ia supernovae (SNe Ia) that were disco...

CCD U BV RI photometry is presented for type IIn SN 2005kd. The maximum luminosity exceeded MV = −19.8, and SN remained brighter than −18 mag for about 400 days. While overall photometric evolution is quite similar to SN 1997cy, SN 2005kd shows a plateau at phases between 119 and 311 days past explosion, which is a unique feature for SN IIn.

Irinotecan (CPT-11) is a promising antitumor agent, recently approved for use in patients with metastatic colorectal cancer. Its active metabolite, SN-38, is glucuronidated by hepatic uridine diphosphate glucuronosyltransferases (UGTs). The major dose-limiting toxicity of irinotecan therapy is diarrhea, which is believed to be secondary to the biliary excretion of SN-38, the extent of which is ...

Cu₆Sn₅ whiskers precipitated in Sn3.0Ag0.5Cu/Cu interconnection in concentrator silicon solar cells solder layer were found and investigated after reflow soldering and during aging. Ag₃Sn fibers can be observed around Cu₆Sn₅ whiskers in the matrix microstructure, which can play an active effect on the reliability of interconnection. Different morphologies of Cu₆Sn₅ whiskers can be observed, and...

A hydro code coupled with radiation transfer was applied to produce monochromatic light curves of two models of type II supernovae (SN II) simulating SN II-P and SN IIb (SN 1993J-like). We then used these template light curves to evaluate the possibility of detecting SNe II at different redshifts. With a 5 hour exposure at VLT/FORS the SN II-P model may be detected at z = 1. However, since our ...

Proof. To see L2-convergence, we will prove that (Sn)n>1 is Cauchy in L 2. It is enough to show that ||Sn − Sm||2 < ε for all n,m > N(ε). Suppose n > m, then we obtain ||Sn − Sm||2 = E(Sn − Sm) = E(Xm+1 +Xm+2 + · · ·+Xn) = Var(Xm+1 +Xm+2 + · · ·+Xn) = Var(Xm+1) + Var(Xm+2) + · · ·+ Var(Xn). For any ε > 0, there exists N = N(ε) with ∑∞ i=N Var(Xi) < ε 2, thus we have ||Sn−Sm||2 < ε for all n,m >...

One of the dose-limiting toxicities of irinotecan (CPT-11) is delayed-onset diarrhea, which is the greatest barrier to treatment with CPT-11-containing regimens. CPT-11 is converted to its active metabolite, SN-38, which is conjugated by hepatic uridine diphosphate glucuronosyl transferase to SN-38 glucuronide (SN-38G). SN-38G, once excreted in the intestinal lumen via bile, is extensively deco...

Recent studies in Aplysia have revealed a novel postsynaptic Ca(2+) component to posttetanic potentiation (PTP) at the siphon sensory to motor neuron (SN-MN) synapse. Here we asked whether the postsynaptic Ca(2+) component of PTP was a special feature of the SN-MN synapse, and if so, whether it reflected a unique property of the SN or the MN. We examined whether postsynaptic injection of BAPTA ...