Plantago ovata is a medicinal plant of plantain, Plantaginaceae, family used to treat intestinal disorders and stomach diseases. P. ovata grain has relieving effects and healing inflammation and irritation of the mucous layer of stomach and duodenal ulcer. Beside the medicinal benefits, this plant is useful for water turbidity removal. Coagulation and flocculation are important processes in wat...

The influence of treatment duration (7 or 14 days) with Plantago ovata husk/levodopa/carbidopa in the bioavailability and other pharmacokinetic parameters of levodopa were evaluated in rabbits. Fiber was administered at two different doses, 100 and 400 mg/kg, and the dosage of levodopa/carbidopa was 20:5 mg/kg. These doses were administered once a day. When 100 mg/kg of fiber was administered, ...

Gastrointestinal dysfunction is common in Parkinson's disease. Fiber therapy could be used to reduce the symptoms of gastrointestinal motility disorders. In a previous study, we showed that slowed gastrointestinal motility modified levodopa pharmacokinetics: area under the plasma concentration-time curve (AUC) and maximum plasma concentration (C(max)) decreased and the elimination was delayed. ...

Fiber formulations are used in human nutrition owing to their beneficial properties for health. It is probable that ingestion of fiber coincides with the oral administration of drugs, and a modification of its oral absorption, and therefore of its pharmacokinetics, can appear. In the present study, the compartmental and noncompartmental pharmacokinetic parameters of ethinylestradiol (EE) in rab...

Consumption of herbal plants as a remedy to relieve the side effects of fat rich diets is on rise currently. The present study was conducted to scrutinize the impact of fat and fat reducing herbal agents on the serum proteins of Rattus norvegicus. Four groups of adult (A) & weaning (W) R. norvegicus one control and three experimental groups were designated as 0, I, II and III and were fed on ra...