The purpose of this study was to examine whether the heart rate (HR) deflection point (HRDP) in the HR-power relationship is concomitant with the maximal stroke volume (SV(max)) value achievement in endurance-trained subjects. Twenty-two international male cyclists (30.3 +/- 7.3 yr, 179.7 +/- 7.2 cm, 71.3 +/- 5.5 kg) undertook a graded cycling exercise (50 W every 3 min) in the upright position...

To determine if expression of mutant p21 ras could convert Simian Virus 40-immortalized human uroepithelial cell line (SV-HUC) to tumorigenicity, SV-HUC cells were transfected with pSV2-neo (a neomycin-resistant gene) or PREJ/ras (c-HA-ras-1 with the 12th codon mutation and neo). Seven independent G418-resistant clones (A----G) were isolated from each group (SV-HUC/ras and SV-HUC/neo). SV-HUC/r...

Discrete-time stochastic volatility (SV) models have generated a considerable literature in financial econometrics. However, carrying out inference for these models is a difficult task and often relies on carefully customized Markov chain Monte Carlo techniques. Our contribution here is twofold. First, we propose a new SV model, namely SV–GARCH, which bridges the gap between SV and GARCH models...

Children with sickle cell anemia (SCA) carry a 200-fold increased risk for cerebral infarction. Stroke can be the result of small-vessel (SV) or large-vessel (LV) disease. However, it is unknown whether these subtypes result from the same pathophysiologic processes. Complete HLA genotyping was performed on 231 eligible children previously enrolled in the Cooperative Study of Sickle Cell Disease...

Postprandial hypotension (PPH) occurs frequently and is thought to reflect an inadequate increase in cardiac output to compensate for the rise in splanchnic blood flow after a meal. Gastric distension by water attenuates the postprandial fall in blood pressure (BP). Cardiac hemodynamics (stroke volume (SV), cardiac output (CO), and global longitudinal strain (GLS)) have hitherto not been measur...

PURPOSE Waldenström's macroglobulinemia (WM) is characterized by an overproduction of immunoglobulin M (IgM), which can lead to a hyperviscosity syndrome (HVS) and HVS-related retinopathy. Plasmapheresis is known to reduce serum viscosity (SV) and IgM levels. The purpose of this study was to investigate the effects of plasmapheresis on HVS-related retinopathy and retinal hemodynamic parameters ...

The REAL-AF registry is a prospective multi-center designed to obtain real-world clinical experience of atrial fibrillation (AF) ablations. HFLTV and JET ventilation have both been shown improve acute procedural efficacy catheter stability compared SV. FPI has be predictor long-term freedom from AF. To date, results not directly compared. report PE metrics during paroxysmal (PAF) persistent (Ps...

Unfortunately, the incorrect version of [1, Theorem 4.3] was published. The correct version of [1, Theorem 4.3] is given in this paper. By employing the generalized higher-order contingent derivatives of set-valued maps, Wang et al. [1] established a sufficient optimality condition of weakly efficient solutions for (SV P): (SV P) min F(x), s.t. G(x) (−D) = ∅, x ∈ E. Theorem 1 (see [1, Theorem 4...

sodium valproate (sv), an antiepileptic drug has several mechanism of action. it inhibits voltage sensitive na+ channels and reduces intracellular na accumulation. these actions are similar to that of both phenytoin and carbamazepine. we have investigated the direct cardiac action of sv and its effects on ouabain-induced arrhythmia in isolated guinea-pig atria. the guinea-pig atrium was dissect...

We characterized the cardiovascular responses to forearm muscle metaboreflex activation during hypercapnia. Ten healthy males participated under three experimental conditions: 1) hypercapnia (HCA, PetCO2 : +10 mmHg, by inhalation of a CO2-enriched gas mixture); 2) muscle metaboreflex activation (MMA, by 5 min of local circulatory occlusion after 1 min of 50% maximum voluntary contraction isomet...