Dynamic Economic Dispatch (DED) plays a vital role in power generation, operation and control. It is a complicated, non-linear constrained problem. In this paper, Maclaurin series based Lagrangian method (MSL) is used to solve the DED problem for generating units with valve-point effect, considering the ramp rate limits. Using Maclaurin series, the sine term used to model the valve-point effect...

Background Myocardial fiber structure exhibits a helical geometry, characterized by the helical angle (HA). HA transitions smoothly from a negative helix in the epicardium to a positive helix in the endocardium. HA plays an important role in understanding the electrical and mechanical properties of the heart. Therefore, there exists a need to non-invasively quantify HA which can be determined u...

Fas-associated death domain (DD) adaptor (FADD), a member of the DD superfamily, contains both a DD and a death effector domain (DED) that are important in mediating FAS ligand-induced apoptotic signaling. P45 is a unique member of the DD superfamily in that it has a domain with sequence and structural characteristics of both DD and DED. We show that p45 forms a complex with FADD and diminishes...

In this article, we will derive closed-form expressions of false alarm probabilities for a given threshold for the dimension estimation-based detector (DED) using Akaike information criterion (AIC) and the minimum description length (MDL) criterion. Specifically, the DED algorithm will be formulated as a binary hypothesis test using AIC and MDL curves. Based on the proposed statistic test, we w...

C ell death by apoptosis is a tightly regulated physiological process that enables the elimination of unwanted cells. It is crucial for embryonic development and the maintenance of tissue homeostasis, but also for defense against certain infectious diseases and cancer. Apoptosis can be triggered from outside the cell, generally after cell–cell contact, by a family of transmembrane proteins call...

IMPORTANCE The immunopathogenic mechanisms of dry eye disease (DED), one of the most common ophthalmic conditions, is incompletely understood. Data from this prospective, double-masked, randomized trial demonstrate that targeting interleukin 1 (IL-1) by topical application of an IL-1 antagonist is efficacious in significantly reducing DED-related patient symptoms and corneal epitheliopathy. O...

OBJECTIVES In some acute-care settings, practitioners are reluctant to institute bronchodilator therapy with metered-dose inhalers (MDIs) as standard management. Such therapy requires that personnel ensure optimal use of these devices. We prospectively evaluated the time required to teach patients correct inhaler use for the emergency treatment of asthma and COPD, and patient factors associated...

PURPOSE The goal of this study was to evaluate the effect of thermal pulsation treatment on tear film parameters, specifically osmolarity and matrix metalloproteinase-9 (MMP-9), in patients with meibomian gland dysfunction (MGD) and dry eye disease (DED). METHODS A single-center review of 189 eyes that underwent thermal pulsation treatment was performed. Data were collected on pre and posttre...

PURPOSE To assess the diagnostic performance of a novel, automated, noninvasive measure of tear film stability derived from Placido disc videokeratography, the tear film surface quality breakup time (TFSQ-BUT), as a clinical marker for diagnosing dry eye disease (DED) relative to a standard of tear hyperosmolarity. METHODS This prospective, cross-sectional study involved 45 participants (28 D...

The development of dermal equivalents (DEs) for the treatment of burns has contributed toward efficient wound closure. A collagen-glycosaminoglycan DE (C-GAG) grafted with hair follicles converted a full-thickness wound to partial-thickness resulting in complete wound closure and restored hair. In this study we compared the ability of both intact pilosebaceous units (PSU) or truncated hair foll...