نتایج جستجو برای: تیره boraginaceae sstr
تعداد نتایج: 4712 فیلتر نتایج به سال:
Ligand binding to somatostatin receptors induces receptor-specific oligomer formation in live cells.
Heptahelical receptors (HHRs) are generally thought to function as monomeric entities. Several HHRs such as somatostatin receptors (SSTRs), however, form homo- and heterooligomers when activated by ligand binding. By using dual fluorescent ligands simultaneously applied to live cells monotransfected with SSTR5 (R5) or SSTR1 (R1), or cotransfected with R5 and R1, we have analyzed the ligand rece...
ویژگیهای دانه گرده 43 گونه متعلق به 32 جنس از تیره گاوزبان با استفاده از میکروسکوپ الکترونی اسکن و بعضی مواقع با میکروسکوپ نوری مورد بررسی قرار گرفته است. نتایج حاصله نشان می دهد که تعداد زیادی از گونه ها با صفات گرده شناسی از یکدیگر تشخیص داده می شوند (eurypalinous). نتایج دیرینه شناسی مشخص می کند که دانه گرده از شکل 3 شیار- روزنی شروع و سایر اشکال از آن مشتق می شوند و در مراحل اولیه به دو گرو...
Use of molecular targeted agents for the diagnosis, staging and therapy of neuroendocrine malignancy
Imaging of neuroendocrine tumours (NET) poses significant challenges because of the heterogeneous biology of the tumours that are represented by this class of neoplasia. NET can range from benign lesions to highly aggressive cancers. Structural imaging techniques have suboptimal sensitivity in most published series and diagnosis is often delayed until metastatic disease is present. Current guid...
Somatostatin receptors (SSTR1-5) mediate antiproliferative effects. In C6 rat glioma cells, somatostatin is cytostatic in vitro via phosphotyrosine phosphatase-dependent inhibition of ERK1/2 activity mediated by SSTR1, -2, and -5. Here we analyzed the effects of SSTR activation on C6 glioma growth in vivo and the intracellular mechanisms involved, comparing somatostatin effects with selective a...
Somatostatin (SRIF) analogs have been employed in medical therapy of non-functioning pituitary adenomas (NFA), with contrasting results. Previous evidence showed that SRIF can exert its antiproliferative effects by reducing vascular endothelial growth factor (VEGF) secretion and action, and that VEGF expression may be related to pituitary tumor growth. The aim of our study was to clarify the po...
Liver resections for hepatocellular carcinoma (HCC) in cirrhotic livers are associated with early recurrence and poor survival. Somatostatin analogues (SSAs) have been reported to inhibit cell proliferation by interacting with specific somatostatin receptors (SSTRs) 2 and 5. The present study investigated whether SSTR expression in HCC was associated with the clinical outcome following octreoti...
Recent data suggest that somatostatin receptors (SSTRs) are expressed on various tumor cells. High-level expression of SSTR on the tumor cell surface provides the basis for the successful clinical use of radiolabeled ligands for the in vivo localization of tumor sites. We have characterized the in vitro binding properties of the novel SSTR ligand 99mTc-P829 using primary human tumors (carcinoid...
Zesius chrysomallus Hübner, 1819 – The Redspot is rediscovered from Varanasi area in Uttar Pradesh State after 108 years. Cordia dichotoma G. Forst, 1786 of Boraginaceae family new addition to list larval host plants India.
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