Transforming growth factor-beta2-treated Ag-pulsed APC mimic APC from the immune privileged eye, and provide signals that generate regulatory T (Tr) cells and mediate peripheral tolerance. We postulated that TGF-beta2-treated Ag-pulsed APC (tolerogenic APC (tol-APC)) might also orchestrate regulation of immune mediated pathogenesis in nonimmune privileged tissues such as the lung. We used an ad...

Controlling variations in plasma membrane (PM) protein abundance is of utmost importance for development in higher plants. For modulating PM protein activity, endocytosed proteins can be either cycled between PM and endosomes or sorted for their irreversible inactivation to lysosomes/vacuoles. Cargo ubiquitination triggers vacuolar delivery for degradation, which is controlled by Endosomal Sort...

WR211 and WR216 are derivatives of halobenzoate-degrading Pseudomonas sp. strain B13 into which the 117-kilobase TOL degradative plasmid pWW0 has been transferred from Pseudomonas putida mt-2. WR211 has lost the ability to grow on the TOL-specific substrate m-xylene but retains the ability to grow on its metabolite, m-toluate. An analysis of the induction of enzymes was consistent with WR211 ca...

Pemerintah kini sedang gencar membangun berbagai infrastruktur untuk mewujudkan pemerataan pembangunan antar daerah, salah satunya jalan tol. Jalan tol dan raya umumnya dihubungkan dengan simpang susun. Salah satu susun yang berlangsung adalah proyek Tol Yogyakarta–Bawen. Dalam perancangan ini, Yogyakarta–Bawen belum memiliki rancangan mendetail, akan dirancang susunnya agar sustainable tidak m...

The gold(III) methoxide complex (C∧N∧C)AuOMe (1) reacts with tris(p-tolyl)phosphine in benzene at room temperature under O abstraction to give the methylgold product (C∧N∧C)AuMe (2) together with O=P(p-tol)3 ((C∧N∧C) = [2,6-(C6H3t Bu-4)2pyridine]2-). Calculations show that this reaction is energetically favorable (ΔG = -32.3 kcal mol-1). The side products in this reaction, the Au(II) complex [A...

This study examines the motor skills and executive functioning (EF) of 28 children diagnosed with pervasive developmental disorder-not otherwise specified (PDD-NOS; mean age: 10 years 6 months, range: 7–12 years; 19 boys, 9 girls) in comparison with ageand gender-matched typically developing children. The potential relationship between motor performance and EF in children with PDD-NOS is invest...