The third-integer coupling resonance at ν(x)-2ν(z)=ℓ, known as the Walkinshaw resonance, is important in high-power accelerators. We find that, when the betatron tunes ramp through a Walkinshaw resonance the fractional emittance growth (FEG) is a universal function of the effective resonance strength: G(1,-2,ℓ)√[ε(xi)]|Δ(ν(x)-2ν(z))/Δn|(-1/2), where G(1,-2,ℓ) is the resonance strength; ε(xi) an...

In wave chaotic scattering, statistical fluctuations of the scattering matrix S and the impedance matrix Z depend both on universal properties and on nonuniversal details of how the scatterer is coupled to external channels. This paper considers the impedance and scattering variance ratios, Xi(z) and Xi(s), where Xi(z) = Var[Z(ij)]/{Var[Z(ii)]Var[Z(jj)]}1/2, Xi(s) = Var[S(ij)]/{Var[S(ii)]Var[S(...

Factor XI deficiency is associated with a bleeding diathesis, but factor XII deficiency is not, indicating that, in normal hemostasis, factor XI must be activated in vivo by a protease other than factor XIIa. Several groups have identified thrombin as the most likely activator of factor XI, although this reaction is slow in solution. Although certain nonphysiologic anionic polymers and surfaces...

Molecular mechanisms controlling the assembly of cartilage-specific types II, IX and XI collagens into a heteropolymeric network of uniformly thin, unbanded fibrils are not well understood, but collagen XI has been implicated. The present study on cartilage from the homozygous chondrodysplasia (cho/cho) mouse adds support to this concept. In the absence of alpha1(XI) collagen chains, thick, ban...

To elucidate the role of charged groups in expression of factor XI coagulant activity, the charged groups of purified human blood coagulation factor XI/XIa containing 125I-XI/XIa were derivatized: free amino groups by succinylation, guanido groups of arginine by reaction with phenylglyoxal hydrate, and free carboxyl groups by reaction with ethylenediamine. The modified proteins were tested for:...

The LHCb collaboration newly measured the decay rate of doubly charmed baryon $\Xi^{++}_{cc}\to\Xi^{'+}\pi^+$ and a ratio its branching fraction with respect to that $\Xi^{++}_{cc}\to\Xi^{+}\pi^+$ is reported as $1.41\pm 0.17\pm 0.10$. This result conflicts theoretical predictions made by several groups. In our previous work, following prescription given in early literature where $us$ diquark $...

Abstract All statistical measurements which represent the values of useful unknown quantities have a realm that is both finite and discrete. Thus our uncertainties about any measurement can be represented by discrete probability mass functions. Nonetheless, common statistical practice treats probability distributions as representable by continuous densities or mixture densities. Many statistica...

Synaptotagmins (Syts) are a group of type I membrane proteins that regulate vesicle docking and fusion in processes such as exocytosis and phagocytosis. All Syts possess a single transmembrane domain, and two conserved tandem Ca(2+)-binding C2 domains. However, Syts IV and XI possess a conserved serine in their C2A domain that precludes these Syts from binding Ca(2+) and phospholipids, and from...

Breast cancer, early onset 1 (BRCA1) encodes a nuclear protein that participates in breast and ovarian cancer suppression. The molecular basis for the gender and tissue specificity of the BRCA1 cancer syndrome is unknown. Recently, we observed that a fraction of BRCA1 in female cells is localized on the inactive X chromosome (Xi). Chromatin immunoprecipitation (ChIP) experiments have demonstrat...

gp(X) = {x1 x2 2 . . . x n n | xi ∈ X, i = ±1} Définition 1.1. Soit X un ensemble. Un produit (ou suite) w = x1 x2 2 . . . x n n , | xi ∈ X, i = ±1 s’appelle un X–mot (ou mot) de longueur n. Si on considère les xi comme des éléments du groupe G, ce mot a une valeur g dans G, et nous écrivons x1 x2 2 . . . x n n =G g (certains écrivent w). Définition 1.2. On dit que le X–mot w = x1 x2 2 . . . x ...