نتایج جستجو برای: شناورسازی با هوای محلول daf

تعداد نتایج: 672902  

2014
Jennifer M. A. Tullet Caroline Araiz Matthew J. Sanders Catherine Au Alexandre Benedetto Irene Papatheodorou Emily Clark Kathrin Schmeisser Daniel Jones Eugene F. Schuster Janet M. Thornton David Gems

The DAF-16/FoxO transcription factor controls growth, metabolism and aging in Caenorhabditis elegans. The large number of genes that it regulates has been an obstacle to understanding its function. However, recent analysis of transcript and chromatin profiling implies that DAF-16 regulates relatively few genes directly, and that many of these encode other regulatory proteins. We have investigat...

Journal: :Blood 1985
A Nicholson-Weller J P March C E Rosen D B Spicer K F Austen

The decay-accelerating factor (DAF), an integral membrane protein of approximately 75,000 mol wt that regulates the stability of the C3 convertases of the classical and alternative complement pathways, was initially isolated from normal erythrocyte stroma and used to prepare a polyclonal antiserum. Previously, anti-DAF antiserum has been used to immunoprecipitate DAF from surface-labeled normal...

Journal: : 2022

سابقه و هدف: امروزه با گسترش فعالیت واحدهای صنعتی، غلظت آلاینده­ ها در هوا افزایش یافته انسان­ از طریق تنفس، بلعیدن جذب پوستی معرض آن­ها قرار می­ گیرند. میان تمام آلاینده ­ها، فلزات سنگین به دلیل ماهیت سمی خود بسیار مورد توجه متخصصان زیست ­محیطی گرفته ­اند. بالای محیط ­زیست، می ­تواند خطر اثرات نامطلوب بر سلامتی انسان را دهد. شهرک صنعتی ناجی زنجان ریخته ­گری مس آلیاژهای آن، ­عنوان یکی منابع انت...

Journal: :Molecular cell 2004
Muneesh Tewari Patrick J Hu Jin Sook Ahn Nono Ayivi-Guedehoussou Pierre-Olivier Vidalain Siming Li Stuart Milstein Chris M Armstrong Mike Boxem Maurice D Butler Svetlana Busiguina Jean-François Rual Nieves Ibarrola Sabrina T Chaklos Nicolas Bertin Philippe Vaglio Mark L Edgley Kevin V King Patrice S Albert Jean Vandenhaute Akhilesh Pandey Donald L Riddle Gary Ruvkun Marc Vidal

To initiate a system-level analysis of C. elegans DAF-7/TGF-beta signaling, we combined interactome mapping with single and double genetic perturbations. Yeast two-hybrid (Y2H) screens starting with known DAF-7/TGF-beta pathway components defined a network of 71 interactions among 59 proteins. Coaffinity purification (co-AP) assays in mammalian cells confirmed the overall quality of this networ...

2012
Donha Park Karen L. Jones Hyojin Lee Terrance P. Snutch Stefan Taubert Donald L. Riddle

Transforming growth factor β (TGF-β) signaling acts through Smad proteins to play fundamental roles in cell proliferation, differentiation, apoptosis, and metabolism. The Receptor associated Smads (R-Smads) interact with DNA and other nuclear proteins to regulate target gene transcription. Here, we demonstrate that the Caenorhabditis elegans R-Smad DAF-8 partners with the nuclear hormone recept...

چگالی ذرات یکی از پارامترهای موثر بر شناورسازی ذرات می‌باشد. ذرات سنگین‌تر، نیروی گرانشی بیشتری را از نیروی چسبندگی بین حباب-ذره ایجاد می‌کنند و احتمال انفصال ذره از حباب هوا را افزایش می‌دهند. در این پژوهش به منظور بررسی تاثیر چگالی ذرات بر شناورسازی، از دو ماده معدنی کوارتز آلفا و سیلیس آمورف به ترتیب با چگالی 67/2 و 2/2 گرم بر سانتی‌متر مکعب استفاده می‌شود. نتایج حاصل از شناورسازی این ذرات ن...

Journal: :Cell 2006
Daniel L. Motola Carolyn L. Cummins Veerle Rottiers Kamalesh K. Sharma Tingting Li Yong Li Kelly Suino-Powell H. Eric Xu Richard J. Auchus Adam Antebi David J. Mangelsdorf

In response to environmental and dietary cues, the C. elegans orphan nuclear receptor, DAF-12, regulates dauer diapause, reproductive development, fat metabolism, and life span. Despite strong evidence for hormonal control, the identification of the DAF-12 ligand has remained elusive. In this work, we identified two distinct 3-keto-cholestenoic acid metabolites of DAF-9, a cytochrome P450 invol...

2010
Peter Q. Pfordresher Simone Dalla Bella

It is well known that timing of rhythm production is disrupted by delayed auditory feedback (DAF), and that disruption varies with delay length. We tested the hypothesis that disruption depends on the state of the movement trajectory at the onset of DAF. Participants tapped isochronous rhythms at a rate specified by a metronome while hearing DAF (for piano tones) of differing lengths. Motion ca...

Journal: :The Journal of Experimental Medicine 1986
M A Davitz M G Low V Nussenzweig

Decay-accelerating factor (DAF) is a 70,000 Mr membrane protein that inhibits amplification of the complement cascade on the cell surface, and protects cells from damage. Purified DAF can be reincorporated into the membrane of red cells and is functional. DAF is deficient in paroxysmal nocturnal hemoglobinuria (PNH), a disease characterized by increased sensitivity of erythrocytes to complement...

Journal: :Blood 2002
Takashi Miwa Lin Zhou Brendan Hilliard Hector Molina Wen-Chao Song

Decay-accelerating factor (DAF) and CD59 are 2 glycosylphosphatidylinositol-anchored membrane proteins that inhibit complement activation at the C3 and C5b-9 step, respectively. CD59 is considered critical for protecting erythrocytes from spontaneous complement attack, as deficiency of CD59 or CD59/DAF, but not of DAF alone, on human erythrocytes renders them sensitive to complement lysis in pa...

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